Antibodies and antibody-derived molecules are continuously developed as both therapeutic
agents and key reagents for advanced diagnostic investigations. Their application in these …

Over 30 years, the Gram-positive bacterium Priestia megaterium (previously known as
Bacillus megaterium) was systematically developed for biotechnological applications …

In recent years, generative protein sequence models have been developed to sample novel
sequences. However, predicting whether generated proteins will fold and function remains …

Poly (ethylene terephthalate)(PET) is one of the most commonly used plastics worldwide
and its accumulation in the environment is a global problem. PETase from Ideonella …

Signal peptides (SPs) play a crucial role in protein translocation in cells. The development of
large protein language models (PLMs) and prompt-based learning provide a new …

Short (15–30 residue) chains of amino acids at the amino termini of expressed proteins
known as signal peptides (SPs) specify secretion in living cells. We trained an attention …

Bacillus amyloliquefaciens, a Gram-positive bacterium, has emerged as a versatile
microorganism with significant applications in various fields, including industry, medicine …

Plastics, such as the polyethylene terephthalate (PET), are widely used for various industrial
applications, due to their physicochemical properties which are particularly useful in the …

Bacillus subtilis, belonging to the type species of Bacillus, is a type of soil-derived, low% G+
C, endospore-forming Gram-positive bacterium. After the discovery of B. subtilis 168 that …

Gram-negative bacteria are attractive hosts for recombinant protein production because they
are fast growing, easy to manipulate, and genetically stable in large cultures. However, the …