Selenium chemistry for spatio-selective peptide and protein functionalization
The ability to construct a peptide or protein in a spatio-specific manner is of great interest for
therapeutic and biochemical research. However, the various functional groups present in …
therapeutic and biochemical research. However, the various functional groups present in …
Alkyne‐Based Syntheses of Carbo‐and Heterohelicenes
AV Gulevskaya, DI Tonkoglazova - Advanced Synthesis & …, 2022 - Wiley Online Library
Abstract [n] Helicenes are polycyclic aromatic molecules in which n ortho‐condensed
benzene or other aromatic rings give rise to helical chiral and highly conjugated structures …
benzene or other aromatic rings give rise to helical chiral and highly conjugated structures …
Chemoselective copper-mediated modification of selenocysteines in peptides and proteins
Highly valuable bioconjugated molecules must be synthesized through efficient,
chemoselective chemical modifications of peptides and proteins. Herein, we report the …
chemoselective chemical modifications of peptides and proteins. Herein, we report the …
Palladium-Catalyzed Direct Selanylation of Chalcogenophenes and Arenes Assisted by 2-(Methylthio) amide
The direct and selective conversion of a C–H bond into a C–Se bond remains a significant
challenge, which is even more intricate with substrates having an innate regioselectivity …
challenge, which is even more intricate with substrates having an innate regioselectivity …
Nonyl Acridine Orange as a Prospective Photocatalyst in Chalcogenylation of Coumarins and Quinolinones
S Lapcinska, P Dimitrijevs… - The Journal of Organic …, 2022 - ACS Publications
A mild and efficient method for preparation of 3-sulfenyl and 3-selenyl coumarins and
quinolinones mediated by artificial light or sunlight is presented. The elaborated protocol …
quinolinones mediated by artificial light or sunlight is presented. The elaborated protocol …
Diorganyl dichalcogenides and copper/iron salts: Versatile cyclization system to achieve carbo-and heterocycles from alkynes
CK Jurinic, AL Belladona, RF Schumacher… - Synthesis, 2021 - thieme-connect.com
Organochalcogen-containing cyclic molecules have shown several promising
pharmacological properties. Consequently, different strategies have been developed for …
pharmacological properties. Consequently, different strategies have been developed for …
Copper (ii)-mediated C–H sulphenylation or selenylation of tryptophan enabling macrocyclization of peptides
D Kobayashi, Y Kohmura, J Hayashi… - Chemical …, 2021 - pubs.rsc.org
Cu (II)-mediated C–H sulphenylation or selenylation of Trp indole by a derivative of cysteine
or selenocysteine enables access to the tryptathionine unit or its selenium congener. The …
or selenocysteine enables access to the tryptathionine unit or its selenium congener. The …
Investigations into the Aqueous Synthesis of Selenoglycoconjugates
D Lim, F Paradisi - European Journal of Organic Chemistry, 2023 - Wiley Online Library
Glycosylation of bioactive molecules has been found to improve the pharmacokinetic
properties of the parent molecule. However, their syntheses often require tedious protecting …
properties of the parent molecule. However, their syntheses often require tedious protecting …
Selenium in peptide chemistry
Ö Pehlivan, M Waliczek, M Kijewska, P Stefanowicz - Molecules, 2023 - mdpi.com
In recent years, researchers have been exploring the potential of incorporating selenium into
peptides, as this element possesses unique properties that can enhance the reactivity of …
peptides, as this element possesses unique properties that can enhance the reactivity of …
Selanyl and tellanyl electrophiles as a driving force in the construction of sophisticated polyaromatic hydrocarbons
P Arsenyan, A Petrenko, S Belyakov - New Journal of Chemistry, 2021 - pubs.rsc.org
Herein, we report the first examples of N-polyaromatic compounds bearing up to 13 fused
aromatic rings, including 23H-benzo [12, 1] tetrapheno [8, 9-b] benzo [12, 1] tetrapheno [9, 8 …
aromatic rings, including 23H-benzo [12, 1] tetrapheno [8, 9-b] benzo [12, 1] tetrapheno [9, 8 …