The impact of vitamin D on cancer: A mini review
In this review, we summarize the most recent advances in vitamin D cancer research to
provide molecular clarity, as well as its translational trajectory across the cancer landscape …
provide molecular clarity, as well as its translational trajectory across the cancer landscape …
[HTML][HTML] The crisscross between p53 and metabolism in cancer: The crisscross between p53 and metabolism in cancer
As the guardian of the genome, p53 is well known for its tumor suppressor function in
humans, controlling cell proliferation, senescence, DNA repair and cell death in cancer …
humans, controlling cell proliferation, senescence, DNA repair and cell death in cancer …
[HTML][HTML] Advances in biomedical applications of vitamin D for VDR targeted management of obesity and cancer
Abstract Background 1, 25 (OH) 2 D 3 is a fat-soluble vitamin, involved in regulating Ca 2+
homeostasis in the body. Its storage in adipose tissue depends on the fat content of the …
homeostasis in the body. Its storage in adipose tissue depends on the fat content of the …
Epigenetic regulation in cancer therapy: From mechanisms to clinical advances
L Tao, Y Zhou, Y Luo, J Qiu, Y Xiao, J Zou… - MedComm …, 2024 - Wiley Online Library
Epigenetic regulation refers to the alteration of gene expression independent of changes in
DNA sequence. It involves chemical modifications such as DNA methylation, histone …
DNA sequence. It involves chemical modifications such as DNA methylation, histone …
p53 转录调控靶基因GGT6 对人结肠癌的影响
柳子朝， 杜文静， 李莉 - 基础医学与临床, 2023 - journal11.magtechjournal.com
目的筛选出p53 转录调控靶基因, 并利用生物信息学分析该基因在结肠癌(COAD) 中的作用.
方法对p53 蛋白稳定剂Nutlin 处理的结肠癌细胞系HCT116 的RNA-seq 数据进行基因差异分析 …
方法对p53 蛋白稳定剂Nutlin 处理的结肠癌细胞系HCT116 的RNA-seq 数据进行基因差异分析 …
[HTML][HTML] Doxorubicin Attenuates Free Fatty Acid-Induced Lipid Accumulation via Stimulation of p53 in HepG2 Cells
C Yun, SH Kim, D Kwon, MR Byun… - Biomolecules & …, 2024 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is characterized by excessive accumulation of fat
in the liver, and there is a global increase in its incidence owing to changes in lifestyle and …
in the liver, and there is a global increase in its incidence owing to changes in lifestyle and …
Development and experimental validation of a folate metabolism-related gene signature to predict the prognosis and immunotherapeutic sensitivity in bladder cancer
X Liu, C Chen, P Xu, B Chen, A Xu, C Liu - Functional & Integrative …, 2023 - Springer
Folate metabolism is critical for the maintenance of genomic stability due to its regulatory
ability to methylation, nucleotide metabolism, and reduction capabilities in cancer cells …
ability to methylation, nucleotide metabolism, and reduction capabilities in cancer cells …
Effect of p53 transcriptional regulatory target gene GGT6 in human colon adenocarcinoma
Z LIU, W DU, L LI - Basic & Clinical Medicine, 2023 - journal11.magtechjournal.com
Objective To screen out a transcriptional target gene of p53 regulation, and to analyze the
role of this gene in colon adenocarcinoma (COAD) by bioinformatics. Methods RNA-seq …
role of this gene in colon adenocarcinoma (COAD) by bioinformatics. Methods RNA-seq …
[HTML][HTML] SHORT COMMUNICATION VHL-dependence of EHHADH Expression in a Human Renal Cell Carcinoma Cell Line
JF Pilz, M Klein, E Neumann-Haefelin, A Ganner - jkcvhl.com
Abstract The von Hippel-Lindau tumor suppressor gene (VHL) is mutated in up to 90% of
clear cell renal cell carcinoma (ccRCC) cases, thus playing a key role in ccRCC …
clear cell renal cell carcinoma (ccRCC) cases, thus playing a key role in ccRCC …
[HTML][HTML] VHL-dependence of EHHADH Expression in a Human Renal Cell Carcinoma Cell Line
JF Pilz, M Klein, E Neumann-Haefelin… - Journal of Kidney …, 2024 - ncbi.nlm.nih.gov
Abstract The von Hippel-Lindau tumor suppressor gene (VHL) is mutated in up to 90% of
clear cell renal cell carcinoma (ccRCC) cases, thus playing a key role in ccRCC …
clear cell renal cell carcinoma (ccRCC) cases, thus playing a key role in ccRCC …