Breast cancer (BC) is a kind of malignant cancer in women, and it has become the most
diagnosed cancer worldwide since 2020. Histone methylation is a common biological …

Genetic aberration including mutation in oncogenes and tumor suppressor genes transforms
normal cells into tumor cells. Epigenetic modifications work concertedly with genetic factors …

Many natural products can exert anticancer or chemopreventive activity by interfering with
the cellular epigenetic machinery. Many studies indicate the relevance of affecting DNA …

Metastasis is an obstacle to the clinical treatment of aggressive breast cancer (BC). Studies
have shown that high mobility group A1 (HMGA1) is abnormally expressed in various …

Cancer stem cells (CSCs) are in general characterized by higher resistance to cell death
and cancer therapies than non-stem differentiated cancer cells. However, we and others …

Cancer-associated fibroblasts (CAFs) are key contributors to ovarian cancer (OC)
progression and therapeutic resistance through dysregulation of the extracellular matrix …

Triple‐negative breast cancer (TNBC) is a highly aggressive and metastatic malignancy with
poor treatment outcomes. The interaction between the tumor microenvironment (TME) and …

Breast cancer, a heterogeneous and intricate disease, ranks among the leading causes of
mortality in women. Restricted therapeutic choices, drug resistance, recurrence, and …

With increase in cancer incidences, alternative strategies for disease management are of
utmost importance. Carbazole, is a compound that is being studied extensively as an anti …

摘要伴随着组蛋白去乙酰化酶抑制剂(histone deacetylase inhibitor, HDACi)
这一类靶向表观遗传调控机制的药物的创新发展, 乳腺癌患者的治疗格局正在被逐渐改变 …