The contribution of natural killer (NK) cells to immunosurveillance of human cancer remains
debatable. Here, we discuss advances in several areas of human NK cell research, many of …

Cell therapy is emerging as a very promising therapeutic modality against cancer,
spearheaded by the clinical success of chimeric antigen receptor (CAR) modified T cells for …

Background Tumor cell-intrinsic mechanisms and complex interactions with the tumor
microenvironment contribute to therapeutic failure via tumor evolution. It may be possible to …

Natural killer (NK) cells are innate cytotoxic lymphoid cells (ILCs) involved in the killing of
infected and tumor cells. Among human and mouse NK cells from the spleen and blood, we …

Purpose: To evaluate the safety, efficacy, and immunobiological correlates of allogeneic NK-
cell–based therapy in primary chemotherapy-refractory or relapsed high-risk …

Natural killer (NK) cells are unique innate lymphoid cells that have therapeutic potential in
adoptive cell transfer-based cancer immunotherapy that has been established across a …

Natural killer (NK) cells hold potential as a source of allogeneic cytotoxic effector cells for
chimeric antigen receptor (CAR)-mediated therapies. Here, we explored the feasibility of …

Background Natural killer (NK) cells hold great promise as a source for allogeneic cell
therapy against hematological malignancies, including acute myeloid leukemia (AML) …

Natural killer (NK) cells have a central role within the innate immune system, eliminating
virally infected, foreign and transformed cells through their natural cytotoxic capacity …

Killer‐cell immunoglobulin‐like receptors (KIR s) are components of two fundamental
biological systems essential for human health and survival. First, they contribute to host …