The use of nanoindentation to determine nanomechanical properties of mineralized tissues
has been investigated extensively. A detailed, critical, and comprehensive review of this …

Osteogenesis imperfecta (OI) is a genetic disorder characterized by an increase in bone
fragility on the macroscopic scale, but few data are available to describe the mechanisms …

As a dedicated experimentalist, John Currey praised the high potential of finite element (FE)
analysis but also recognized its critical limitations. The application of the FE methodology to …

Excessive skeletal deformations and brittle fractures in the vast majority of patients suffering
from osteogenesis imperfecta (OI) are a result of substantially reduced bone quality …

Following traumatic injury, skin has the capacity to repair itself through a complex cascade of
biochemical change. The dermis, which contains a load-bearing collagenous network …

Osteogenesis imperfecta (OI) is a genetic disorder characterized by a change in bone tissue
quality, but little data are available to describe the factors involved at the macroscopic scale …

Based on the theory of composite mechanics, a three-pillar framework “bone mass-
microarchitecture-tissue property” instead of “bone mass-bone quality”, is proposed to …

abstract Osteogenesis imperfecta (OI) is an inheritable, genetic, and collagen‐related
disorder leading to an increase in bone fragility, but the origin of its “brittle behavior” is …

BACKGROUND: Osteogenesis imperfecta is a heterogeneous genetic disorder
characterized by bone fragility. Previous research suggests that impaired collagen network …

Osteogenesis imperfecta (OI) is a genetic, collagen‐related bone disease that increases the
incidence of bone fractures. Still, the origin of this brittle mechanical behavior remains …