Fluorescent dyes based on rhodamine derivatives for bioimaging and therapeutics: recent progress, challenges, and prospects

S Zeng, X Liu, YS Kafuti, H Kim, J Wang… - Chemical Society …, 2023 - pubs.rsc.org
Since their inception, rhodamine dyes have been extensively applied in biotechnology as
fluorescent markers or for the detection of biomolecules owing to their good optical physical …

Controlled anti-cancer drug release through advanced nano-drug delivery systems: Static and dynamic targeting strategies

FM Kashkooli, M Soltani, M Souri - Journal of controlled release, 2020 - Elsevier
Advances in nanomedicine, including early cancer detection, targeted drug delivery, and
personalized approaches to cancer treatment are on the rise. For example, targeted drug …

Tumour acidosis: from the passenger to the driver's seat

C Corbet, O Feron - Nature Reviews Cancer, 2017 - nature.com
The high metabolic demand of cancer cells leads to an accumulation of H+ ions in the
tumour microenvironment. The disorganized tumour vasculature prevents an efficient wash …

How the Warburg effect supports aggressiveness and drug resistance of cancer cells?

P Icard, S Shulman, D Farhat, JM Steyaert… - Drug Resistance …, 2018 - Elsevier
Cancer cells employ both conventional oxidative metabolism and glycolytic anaerobic
metabolism. However, their proliferation is marked by a shift towards increasing glycolytic …

[HTML][HTML] ChatGPT and the rise of generative AI: Threat to academic integrity?

DO Eke - Journal of Responsible Technology, 2023 - Elsevier
The emergence of OpenAI's ChatGPT has put intense spotlight on Generative AI (Gen-AI)
systems and their possible impacts on Academic integrity. This paper provides an overview …

Dysregulated pH: a perfect storm for cancer progression

BA Webb, M Chimenti, MP Jacobson… - Nature Reviews Cancer, 2011 - nature.com
Although cancer is a diverse set of diseases, cancer cells share a number of adaptive
hallmarks. Dysregulated pH is emerging as a hallmark of cancer because cancers show …

Subcellular mechanism of microbial inactivation during water disinfection by cold atmospheric-pressure plasma

H Xu, Y Zhu, M Du, Y Wang, S Ju, R Ma, Z Jiao - Water Research, 2021 - Elsevier
Although the identification of effective reactive oxygen species (ROS) generated by plasma
has been extensively studied, yet the subcellular mechanism of microbial inactivation has …

Cancer cell behaviors mediated by dysregulated pH dynamics at a glance

KA White, BK Grillo-Hill, DL Barber - Journal of cell science, 2017 - journals.biologists.com
Dysregulated pH is a common characteristic of cancer cells, as they have an increased
intracellular pH (pHi) and a decreased extracellular pH (pHe) compared with normal cells …

pH sensing and regulation in cancer

M Damaghi, JW Wojtkowiak, RJ Gillies - Frontiers in physiology, 2013 - frontiersin.org
Cells maintain intracellular pH (pHi) within a narrow range (7.1–7.2) by controlling
membrane proton pumps and transporters whose activity is set by intra-cytoplasmic pH …

Carbonic anhydrases: role in pH control and cancer

MY Mboge, BP Mahon, R McKenna, SC Frost - Metabolites, 2018 - mdpi.com
The pH of the tumor microenvironment drives the metastatic phenotype and
chemotherapeutic resistance of tumors. Understanding the mechanisms underlying this pH …