[HTML][HTML] A review of computational tools for generating metagenome-assembled genomes from metagenomic sequencing data
Metagenomic sequencing provides a culture-independent avenue to investigate the
complex microbial communities by constructing metagenome-assembled genomes (MAGs) …
complex microbial communities by constructing metagenome-assembled genomes (MAGs) …
[HTML][HTML] From molecules to genomic variations: Accelerating genome analysis via intelligent algorithms and architectures
We now need more than ever to make genome analysis more intelligent. We need to read,
analyze, and interpret our genomes not only quickly, but also accurately and efficiently …
analyze, and interpret our genomes not only quickly, but also accurately and efficiently …
Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states
H Song, HNW Weinstein, P Allegakoen… - Nature …, 2022 - nature.com
Prostate cancer is the second most common malignancy in men worldwide and consists of a
mixture of tumor and non-tumor cell types. To characterize the prostate cancer tumor …
mixture of tumor and non-tumor cell types. To characterize the prostate cancer tumor …
[HTML][HTML] Recommendations for the introduction of metagenomic next-generation sequencing in clinical virology, part II: bioinformatic analysis and reporting
Metagenomic next-generation sequencing (mNGS) is an untargeted technique for
determination of microbial DNA/RNA sequences in a variety of sample types from patients …
determination of microbial DNA/RNA sequences in a variety of sample types from patients …
Bladder cancer organoids as a functional system to model different disease stages and therapy response
M Minoli, T Cantore, D Hanhart, M Kiener… - Nature …, 2023 - nature.com
Abstract Bladder Cancer (BLCa) inter-patient heterogeneity is the primary cause of treatment
failure, suggesting that patients could benefit from a more personalized treatment approach …
failure, suggesting that patients could benefit from a more personalized treatment approach …
Oxford nanopore MinION direct RNA-seq for systems biology
MA Pyatnitskiy, VA Arzumanian, SP Radko, KG Ptitsyn… - Biology, 2021 - mdpi.com
Simple Summary A new technology has been recently developed by Oxford Nanopore
Technologies, enabling researchers to investigate the structure and relative abundance of …
Technologies, enabling researchers to investigate the structure and relative abundance of …
Genetic diversity and spatial distribution of Burkholderia mallei by core genome-based multilocus sequence typing analysis
S Appelt, AM Rohleder, D Jacob, H Von Buttlar… - PLoS …, 2022 - journals.plos.org
Burkholderia mallei is the etiological agent of glanders, a highly contagious and often fatal
disease in equids. Due to the high genetic clonality of B. mallei, high-resolution typing …
disease in equids. Due to the high genetic clonality of B. mallei, high-resolution typing …
Virulence and resistance patterns of Vibrio cholerae non-O1/non-O139 acquired in Germany and other European countries
K Schmidt, HC Scholz, S Appelt, J Michel… - Frontiers in …, 2023 - frontiersin.org
Global warming has caused an increase in the emergence of Vibrio species in marine and
estuarine environments as well as fresh water bodies. Over the past decades, antimicrobial …
estuarine environments as well as fresh water bodies. Over the past decades, antimicrobial …
Microbiome in death and beyond: current vistas and future trends
Forensic medicine has, for a long time, been relying on biochemical, anthropologic, and
histopathologic evidences in solving various investigations. However, depending on the …
histopathologic evidences in solving various investigations. However, depending on the …
Advancing clinical genomics and precision medicine with GVViZ: FAIR bioinformatics platform for variable gene-disease annotation, visualization, and expression …
Background Genetic disposition is considered critical for identifying subjects at high risk for
disease development. Investigating disease-causing and high and low expressed genes …
disease development. Investigating disease-causing and high and low expressed genes …