[HTML][HTML] A review of computational tools for generating metagenome-assembled genomes from metagenomic sequencing data

C Yang, D Chowdhury, Z Zhang, WK Cheung… - Computational and …, 2021 - Elsevier
Metagenomic sequencing provides a culture-independent avenue to investigate the
complex microbial communities by constructing metagenome-assembled genomes (MAGs) …

[HTML][HTML] From molecules to genomic variations: Accelerating genome analysis via intelligent algorithms and architectures

M Alser, J Lindegger, C Firtina, N Almadhoun… - Computational and …, 2022 - Elsevier
We now need more than ever to make genome analysis more intelligent. We need to read,
analyze, and interpret our genomes not only quickly, but also accurately and efficiently …

Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states

H Song, HNW Weinstein, P Allegakoen… - Nature …, 2022 - nature.com
Prostate cancer is the second most common malignancy in men worldwide and consists of a
mixture of tumor and non-tumor cell types. To characterize the prostate cancer tumor …

[HTML][HTML] Recommendations for the introduction of metagenomic next-generation sequencing in clinical virology, part II: bioinformatic analysis and reporting

JJC de Vries, JR Brown, N Couto, M Beer… - Journal of Clinical …, 2021 - Elsevier
Metagenomic next-generation sequencing (mNGS) is an untargeted technique for
determination of microbial DNA/RNA sequences in a variety of sample types from patients …

Bladder cancer organoids as a functional system to model different disease stages and therapy response

M Minoli, T Cantore, D Hanhart, M Kiener… - Nature …, 2023 - nature.com
Abstract Bladder Cancer (BLCa) inter-patient heterogeneity is the primary cause of treatment
failure, suggesting that patients could benefit from a more personalized treatment approach …

Oxford nanopore MinION direct RNA-seq for systems biology

MA Pyatnitskiy, VA Arzumanian, SP Radko, KG Ptitsyn… - Biology, 2021 - mdpi.com
Simple Summary A new technology has been recently developed by Oxford Nanopore
Technologies, enabling researchers to investigate the structure and relative abundance of …

Genetic diversity and spatial distribution of Burkholderia mallei by core genome-based multilocus sequence typing analysis

S Appelt, AM Rohleder, D Jacob, H Von Buttlar… - PLoS …, 2022 - journals.plos.org
Burkholderia mallei is the etiological agent of glanders, a highly contagious and often fatal
disease in equids. Due to the high genetic clonality of B. mallei, high-resolution typing …

Virulence and resistance patterns of Vibrio cholerae non-O1/non-O139 acquired in Germany and other European countries

K Schmidt, HC Scholz, S Appelt, J Michel… - Frontiers in …, 2023 - frontiersin.org
Global warming has caused an increase in the emergence of Vibrio species in marine and
estuarine environments as well as fresh water bodies. Over the past decades, antimicrobial …

Microbiome in death and beyond: current vistas and future trends

D Roy, S Tomo, P Purohit, P Setia - Frontiers in Ecology and …, 2021 - frontiersin.org
Forensic medicine has, for a long time, been relying on biochemical, anthropologic, and
histopathologic evidences in solving various investigations. However, depending on the …

Advancing clinical genomics and precision medicine with GVViZ: FAIR bioinformatics platform for variable gene-disease annotation, visualization, and expression …

Z Ahmed, EG Renart, S Zeeshan, XQ Dong - Human genomics, 2021 - Springer
Background Genetic disposition is considered critical for identifying subjects at high risk for
disease development. Investigating disease-causing and high and low expressed genes …