Bioluminescent assays for ADMET
Bioluminescent assays couple a limiting component of a luciferase-catalyzed photon-
emitting reaction to a variable parameter of interest, while holding the other components …
emitting reaction to a variable parameter of interest, while holding the other components …
Homogeneous, bioluminescent protease assays: caspase-3 as a model
MA O'Brien, WJ Daily, PE Hesselberth, RA Moravec… - SLAS Discovery, 2005 - Elsevier
Using caspase-3 as a model, the authors have developed a strategy for highly sensitive,
homogeneous protease assays suitable for high-throughput, automated applications. The …
homogeneous protease assays suitable for high-throughput, automated applications. The …
[PDF][PDF] D-Luciferin, derivatives and analogues: synthesis and in vitro/in vivo luciferase-catalyzed bioluminescent activity.
G Meroni, M Rajabi, E Santaniello - ARKIVOC: Online Journal of …, 2009 - arkat-usa.org
D-luciferin is the natural substrate of all luciferases that catalyze the production of light in
bioluminescent insects. The present review covers the synthesis of D-luciferin and …
bioluminescent insects. The present review covers the synthesis of D-luciferin and …
Luminogenic and fluorogenic compounds and methods to detect molecules or conditions
JJ Cali, W Daily, E Hawkins, D Klaubert, J Liu… - US Patent …, 2011 - Google Patents
US7951550B2 - Luminogenic and fluorogenic compounds and methods to detect molecules
or conditions - Google Patents US7951550B2 - Luminogenic and fluorogenic compounds and …
or conditions - Google Patents US7951550B2 - Luminogenic and fluorogenic compounds and …
[图书][B] Handbook of assay development in drug discovery
LK Minor - 2006 - books.google.com
The Handbook of Assay Development in Drug Discovery describes all the tools currently
available for performing various assay techniques. Featuring troubleshooting advice for …
available for performing various assay techniques. Featuring troubleshooting advice for …
Luminescence-based methods and probes for measuring cytochrome P450 activity
JJ Cali, D Klaubert, W Daily, SKS Ho… - US Patent …, 2010 - Google Patents
4,826,989 A 5, 1989 Batz et al. 4,992,531 A 2, 1991 Patroni et al................ 530,351
5,035,999 A* 7/1991 Geiger et al....... 435/23 5,098,828 A 3/1992 Geiger et al.... 435/7.72 …
5,035,999 A* 7/1991 Geiger et al....... 435/23 5,098,828 A 3/1992 Geiger et al.... 435/7.72 …
[HTML][HTML] Bioluminescence assay platform for selective and sensitive detection of Ub/Ubl proteases
As the importance of ubiquitylation in certain disease states becomes increasingly apparent,
the enzymes responsible for removal of ubiquitin (Ub) from target proteins, deubiquitylases …
the enzymes responsible for removal of ubiquitin (Ub) from target proteins, deubiquitylases …
Bioluminescent protease assay
M O'brien, KV Wood, D Klaubert, W Daily - US Patent 7,148,030, 2006 - Google Patents
US7148030B2 - Bioluminescent protease assay - Google Patents US7148030B2 -
Bioluminescent protease assay - Google Patents Bioluminescent protease assay Download PDF …
Bioluminescent protease assay - Google Patents Bioluminescent protease assay Download PDF …
A bioluminescent assay for the sensitive detection of proteases
DM Leippe, D Nguyen, M Zhou, T Good… - …, 2011 - Taylor & Francis
A bioluminescent general protease assay was developed using a combination of five
luminogenic peptide substrates. The peptide-conjugated luciferin substrates were combined …
luminogenic peptide substrates. The peptide-conjugated luciferin substrates were combined …
Luminogenic and nonluminogenic multiplex assay
TL Riss, A Niles, RA Moravec - US Patent 7,416,854, 2008 - Google Patents
2019-04-03 Assigned to JPMORGAN CHASE BANK, NA, AS COLLATERAL AGENT
reassignment JPMORGAN CHASE BANK, NA, AS COLLATERAL AGENT SECURITY …
reassignment JPMORGAN CHASE BANK, NA, AS COLLATERAL AGENT SECURITY …