The transition-metal-aided stereoselective construction of sp3-carbon-rich heterocyclic
scaffolds using strained-ring systems has received considerable attention in recent years …

The five-membered, nitrogen-containing pyrroline ring is a privileged structure. This ring is
present in many bioactive compounds from natural sources. Pyrrolines—the dihydro …

The development of (4+ 3) cyclizations of vinyl aziridines, especially catalytic asymmetric
versions, is needed in organic synthesis. This report describes an iridium-catalyzed (4+ 3) …

Chiral γ-lactam-containing skeletons are important motifs in bioactive natural products,
pharmaceuticals, and bioactive molecules. Herein, we report a general and modular …

A robust and scalable formal [4+ 3] annulation reaction for the synthesis of optically pure 1, 4-
benzodiazepinones and 1, 4-benzoxazepinones has been established by a combined …

The synthesis of cyclic imidazolidines via two N–C bond-forming sequences has been
developed. The transformation goes through a (3+ 2)-cycloaddition reaction in the presence …

Aziridines (azacyclopropanes) constitute the well-known class of heterocyclic compounds.
The studies on synthesis and reactivity of aziridines have drawn tremendous interest of …

An expeditious synthetic route to access structurally diverse 1, 4, 5, 6-tetrahydropyrimidines
via domino ring-opening cyclization of activated aziridines with α-acidic isocyanides has …

Highly enantioselective C2 alkylation and inverse-electron-demand [3+ 2]-cycloaddition of 3-
methylindoles with 2, 2′-diester aziridine were accomplished. The chemodivergent …

Novel 3, 4-dihydro-1, 4-benzoxazine derivatives have been synthesized by an efficient and
simple method in excellent enantio-and diastereospecificity (ee> 99%, de> 99%). The …