Viral membrane fusion: a dance between proteins and lipids
There are at least 21 families of enveloped viruses that infect mammals, and many contain
members of high concern for global human health. All enveloped viruses have a dedicated …
members of high concern for global human health. All enveloped viruses have a dedicated …
Visualizing intermediate stages of viral membrane fusion by cryo-electron tomography
SM Kephart, N Hom, KK Lee - Trends in Biochemical Sciences, 2024 - cell.com
Protein-mediated membrane fusion is the dynamic process where specialized protein
machinery undergoes dramatic conformational changes that drive two membrane bilayers …
machinery undergoes dramatic conformational changes that drive two membrane bilayers …
Transient opening of trimeric prefusion RSV F proteins
MSA Gilman, P Furmanova-Hollenstein… - Nature …, 2019 - nature.com
The respiratory syncytial virus (RSV) F glycoprotein is a class I fusion protein that mediates
viral entry and is a major target of neutralizing antibodies. Structures of prefusion forms of …
viral entry and is a major target of neutralizing antibodies. Structures of prefusion forms of …
Structural and cellular biology of rhabdovirus entry
L Belot, A Albertini, Y Gaudin - Advances in virus research, 2019 - Elsevier
Rhabdoviruses are enveloped viruses with a negative-sense single strand RNA genome
and are widespread among a great variety of organisms. In their membrane, they have a …
and are widespread among a great variety of organisms. In their membrane, they have a …
Structural intermediates in the low pH-induced transition of influenza hemagglutinin
The hemagglutinin (HA) glycoproteins of influenza viruses play a key role in binding host
cell receptors and in mediating virus-host cell membrane fusion during virus infection. Upon …
cell receptors and in mediating virus-host cell membrane fusion during virus infection. Upon …
The phenuivirus Toscana virus makes an atypical use of vacuolar acidity to enter host cells
J Koch, Q Xin, M Obr, A Schäfer, N Rolfs… - PLoS …, 2023 - journals.plos.org
Toscana virus is a major cause of arboviral disease in humans in the Mediterranean basin
during summer. However, early virus-host cell interactions and entry mechanisms remain …
during summer. However, early virus-host cell interactions and entry mechanisms remain …
Crystal structure of Mokola virus glycoprotein in its post-fusion conformation
Mokola virus (MOKV) belongs to the lyssavirus genus. As other genus members—including
rabies virus (RABV)—it causes deadly encephalitis in mammals. MOKV entry into host cells …
rabies virus (RABV)—it causes deadly encephalitis in mammals. MOKV entry into host cells …
The stabilities of the soluble ectodomain and fusion peptide hairpins of the Influenza virus hemagglutinin subunit II protein are positively correlated with membrane …
A Ranaweera, PU Ratnayake, DP Weliky - Biochemistry, 2018 - ACS Publications
Cellular entry of influenza virus is mediated by the viral protein hemagglutinin (HA), which
forms an initial complex of three HA1 and three HA2 subunits. Each HA2 includes a fusion …
forms an initial complex of three HA1 and three HA2 subunits. Each HA2 includes a fusion …
[HTML][HTML] Early Virus–Host Cell Interactions
PY Lozach - Journal of Molecular Biology, 2018 - ncbi.nlm.nih.gov
Viruses are particles with diverse shapes and sizes, ranging from a few dozen nanometers
to micrometers. They are made up of repetitive blocks of proteins, and sometimes, lipids and …
to micrometers. They are made up of repetitive blocks of proteins, and sometimes, lipids and …
[PDF][PDF] Inaugural dissertation for obtaining the doctoral degree of the Combined Faculty of Mathematics, Engineering and Natural Sciences
MSJ Koch - bunyavirus.org
The term" zoonosis" is derived from the Greek words" zoon" and" nosos", meaning animal
and illness. According to the World Health Organization (WHO), it includes any disease or …
and illness. According to the World Health Organization (WHO), it includes any disease or …