Single-stranded DNA-binding proteins (SSBs) play vital roles in DNA metabolism. Proteins
of the SSB family exclusively and transiently bind to ssDNA, preventing the DNA double …

Alteration of stress (abiotic and biotic) constitutes one of the major problems for normal
plants health. In the present scenario, new molecular tools are broadly utilized to improve …

Hachiman is a broad-spectrum antiphage defense system of unknown function. We show
here that Hachiman comprises a heterodimeric nuclease-helicase complex, HamAB. HamA …

Most of anti-tumour therapies eliminate neoplastic cells by introducing DNA damage which
ultimately triggers cell death. These effects are counteracted by activated DNA repair …

XPD helicase is a DNA-unwinding enzyme involved in DNA repair. As part of TFIIH, XPD
opens a repair bubble in DNA for access by proteins in the nucleotide excision repair …

A multitude of different types of lesions is continuously introduced into the DNA inside our
cells, and their rapid and efficient repair is fundamentally important for the maintenance of …

Escherichia coli YoaA aids in the resolution of DNA damage that halts DNA synthesis in vivo
in conjunction with χ, an accessory subunit of DNA polymerase III. YoaA and χ form a …

The Escherichia coli XPD/Rad3-like helicase, YoaA, and DNA polymerase III subunit, χ, are
involved in E. coli DNA damage tolerance and repair. YoaA and χ promote tolerance to the …

Helicases are ubiquitous motors involved in almost all aspects of nucleic acid metabolism;
therefore, revealing their unwinding behaviors and mechanisms is fundamentally and …

XPD/Rad3-like helicases are critical genome maintenance enzymes found in all forms of life.
The four human XPD/Rad3-like helicases are involved in various DNA repair pathways and …