Abstract Background Even though 8%‐25% of most populations studied globally are labeled
as penicillin allergic, most diagnoses of penicillin allergy are made in childhood and relate …

Hypersensitivity reactions to betalactams (BLs) are classified as immediate or
nonimmediate. The former usually appear within 1 h of drug‐intake and are mediated by …

Resolving conflict of interest The Joint Task Force on Practice Parameters (JTFPP) is
committed to ensuring that all guidelines are based on the best scientific evidence at the …

A drug provocation test (DPT) is the controlled administration of a drug in order to diagnose
drug hypersensitivity reactions. DPTs are performed under medical surveillance, whether …

Cephalosporins are among the most commonly prescribed antibiotic classes due to their
wide clinical utility and general tolerability, with approximately 1–3% of the population …

Cephalosporins are commonly used antibiotics both in hospitalized patients and in
outpatients. Hypersensitivity reactions to cephalosporins are becoming increasingly …

Drug allergy is one type of adverse reaction to drugs and encompasses a spectrum of
hypersensitivity reactions with heterogeneous mechanisms and clinical presentations. A …

BACKGROUND: The practice of avoiding cephalosporin administration to penicillin-allergic
patients persists despite the low rate of cross reactions between both groups of antibiotics …

Cephalosporin antibiotics are widely prescribed for common infections such as bronchitis,
otitis media, pneumonia, and cellulitis. They are also administered as first-line prophylaxis …

ContextClinicians frequently withhold antibiotics that contain penicillin based on patients'
self-reported clinical history of an adverse reaction to penicillin and the clinicians' own …