The relationship between blood groups and disease

DJ Anstee - Blood, The Journal of the American Society of …, 2010 - ashpublications.org
The relative contribution of founder effects and natural selection to the observed distribution
of human blood groups has been debated since blood group frequencies were shown to …

Immunogenetics of type 1 diabetes: a comprehensive review

JA Noble - Journal of autoimmunity, 2015 - Elsevier
Abstract Type 1 diabetes (T1D) results from the autoimmune destruction of insulin-producing
beta cells in the pancreas. Prevention of T1D will require the ability to detect and modulate …

Distinct diversity of KIR genes in three southern Indian populations: comparison with world populations revealed a link between KIR gene content and pre-historic …

R Rajalingam, Z Du, A Meenagh, L Luo, VJ Kavitha… - Immunogenetics, 2008 - Springer
By interacting with polymorphic HLA class I molecules, the killer cell immunoglobulin-like
receptors (KIR) influence the innate and adaptive immune response to infection. The KIR …

Wheat allergy and intolerence; recent updates and perspectives

I Pasha, F Saeed, MT Sultan, R Batool… - Critical reviews in …, 2016 - Taylor & Francis
The current review paper highlights the complicacies associated with communities relying
on wheat as their dietary staple. Although, wheat is an important source of nutrients but is …

Fifty years of HLA-associated type 1 diabetes risk: history, current knowledge, and future directions

JA Noble - Frontiers in Immunology, 2024 - frontiersin.org
More than 50 years have elapsed since the association of human leukocyte antigens (HLA)
with type 1 diabetes (T1D) was first reported. Since then, methods for identification of HLA …

KIR gene content diversity in four Iranian populations

E Ashouri, S Farjadian, EF Reed, A Ghaderi… - Immunogenetics, 2009 - Springer
Killer cell immunoglobulin-like receptors (KIR) regulate natural killer cell response against
infection and malignancy. KIR genes are variable in the number and type, thereby …

Killer immunoglobulin receptor gene and allele frequencies in Caucasoid, Oriental and Black populations from different continents

D Middleton, A Meenagh, J Moscoso… - Tissue …, 2008 - Wiley Online Library
Parallel to the growth in interest in the past few years in the killer immunoglobulin‐like
receptor (KIR) genes has been the elucidation of the presence/absence of these genes and …

Combination of KIR 2DL2 and HLA‐C1 (Asn80) confers susceptibility to type 1 diabetes in Latvians

A Shastry, SK Sedimbi, R Rajalingam… - International journal …, 2008 - Wiley Online Library
Killer immunoglobulin‐like receptors (KIRs) are known to modulate natural killer (NK) and
NK T‐cell function by interacting with human leucocyte antigen (HLA) class I ligands on …

Killer cell immunoglobulin‐like receptor along with HLA‐C ligand genes are associated with type 1 diabetes in Chinese Han population

D Zhi, C Sun, SK Sedimbi, F Luo… - Diabetes/metabolism …, 2011 - Wiley Online Library
Objective Killer cell immunoglobulin‐like receptor (KIR) genes and their putative ligands
human leukocyte antigen (HLA)‐C genes have been associated with type 1 diabetes (T1D) …

The dysfunction of natural killer cells is essential for the development of type 1 diabetes

S Sabetkam, H Kalarestaghi, Z Mazloumi… - … -Research and Practice, 2023 - Elsevier
Abstract Type 1 diabetes (T1D) is characterized by destruction of pancreatic insulin-
producing beta cells by immune cells. In general, environmental and genetic factors can …