Exercise: a behavioral intervention to enhance brain health and plasticity
CW Cotman, NC Berchtold - Trends in neurosciences, 2002 - cell.com
Extensive research on humans suggests that exercise could have benefits for overall health
and cognitive function, particularly in later life. Recent studies using animal models have …
and cognitive function, particularly in later life. Recent studies using animal models have …
The Parieto-Frontal Integration Theory (P-FIT) of intelligence: converging neuroimaging evidence
“Is there a biology of intelligence which is characteristic of the normal human nervous
system?” Here we review 37 modern neuroimaging studies in an attempt to address this …
system?” Here we review 37 modern neuroimaging studies in an attempt to address this …
Chronic stress weakens connectivity in the prefrontal cortex: architectural and molecular changes
E Woo, LH Sansing, AFT Arnsten, D Datta - Chronic Stress, 2021 - journals.sagepub.com
Chronic exposure to uncontrollable stress causes loss of spines and dendrites in the
prefrontal cortex (PFC), a recently evolved brain region that provides top-down regulation of …
prefrontal cortex (PFC), a recently evolved brain region that provides top-down regulation of …
Structure–stability–function relationships of dendritic spines
H Kasai, M Matsuzaki, J Noguchi, N Yasumatsu… - Trends in …, 2003 - cell.com
Dendritic spines, which receive most of the excitatory synaptic input in the cerebral cortex,
are heterogeneous with regard to their structure, stability and function. Spines with large …
are heterogeneous with regard to their structure, stability and function. Spines with large …
Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2
WG Chen, Q Chang, Y Lin, A Meissner, AE West… - Science, 2003 - science.org
Mutations in MeCP2, which encodes a protein that has been proposed to function as a
global transcriptional repressor, are the cause of Rett syndrome (RT T), an X-linked …
global transcriptional repressor, are the cause of Rett syndrome (RT T), an X-linked …
Calcium regulation of neuronal gene expression
AE West, WG Chen, MB Dalva… - Proceedings of the …, 2001 - National Acad Sciences
Plasticity is a remarkable feature of the brain, allowing neuronal structure and function to
accommodate to patterns of electrical activity. One component of these long-term changes is …
accommodate to patterns of electrical activity. One component of these long-term changes is …
BDNF responses in healthy older persons to 35 minutes of physical exercise, cognitive training, and mindfulness: associations with working memory function
Brain-derived neurotrophic factor (BDNF) has a central role in brain plasticity by mediating
changes in cortical thickness and synaptic density in response to physical activity and …
changes in cortical thickness and synaptic density in response to physical activity and …
From acquisition to consolidation: on the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning
One of the most rigorously investigated problems in modern neuroscience is to decipher the
mechanisms by which experience-induced changes in the central nervous system are …
mechanisms by which experience-induced changes in the central nervous system are …
New insights into brain BDNF function in normal aging and Alzheimer disease
L Tapia-Arancibia, E Aliaga, M Silhol, S Arancibia - Brain research reviews, 2008 - Elsevier
The decline observed during aging involves multiple factors that influence several systems.
It is the case for learning and memory processes which are severely reduced with aging. It is …
It is the case for learning and memory processes which are severely reduced with aging. It is …
Biological mechanisms of physical activity in preventing cognitive decline
I Lista, G Sorrentino - Cellular and molecular neurobiology, 2010 - Springer
In order to guarantee better conditions for competition, the nervous system has developed
not only mechanisms controlling muscle effectors, but also retrograde systems that, starting …
not only mechanisms controlling muscle effectors, but also retrograde systems that, starting …