Nucleic acid amplification technologies (NAATs) have become fundamental tools in
molecular diagnostics, due to their ability to detect small amounts of target molecules. Since …

Rolling circle amplification (RCA) is an isothermal enzymatic process where a short DNA or
RNA primer is amplified to form a long single stranded DNA or RNA using a circular DNA …

Micro-Total Analysis Systems (µTAS) for use in on-site rapid detection of DNA or RNA are
increasingly being developed. Here, amplification of the target sequence is key to increasing …

Rapid and timely diagnosis of infectious diseases is a critical determinant of clinical
outcomes and general public health. For the detection of various pathogens, microfluidics …

The integration of nucleic acids detection assays in microfluidic devices represents a highly
promising approach for the development of convenient, cheap and efficient diagnostic tools …

Enhancing the limit of detection (LOD) is significant for crucial diseases. Cancer
development could take more than 10 years, from one mutant cell to a visible tumor. Early …

Since the development of the polymerase chain reaction (PCR) technique, genomic
information has been retrievable from lesser amounts of DNA than previously possible. PCR …

In the post-human-genome-project era, the development of molecular diagnostic techniques
has advanced the frontiers of biomedical research. Nucleic-acid-based technology (NAT) …

The sensitive detection and quantification of DNA targets in the food industry and in
environmental and clinical settings are issues of utmost importance in ensuring …

Microbead-based technologies represent elegant and versatile approaches for highly
parallelized quantitative multiparameter assays. They also form the basis of various …