Bradykinesia is one of the cardinal motor symptoms of Parkinson's disease and other
parkinsonisms. The various clinical aspects related to bradykinesia and the …

Parkinson's disease is a chronic progressive neurodegenerative disorder characterized by
resting tremor, slowness of movements, rigidity, gait disturbance and postural instability …

People with late-stage Parkinson's disease (PD) often suffer from debilitating locomotor
deficits that are resistant to currently available therapies. To alleviate these deficits, we …

Objective: Parkinson's disease (PD) is a progressive neurological disorder characterised by
a large number of motor and non-motor features that can impact on function to a variable …

Partial least squares (PLS) analysis has been used to characterize distributed signals
measured by neuroimaging methods like positron emission tomography (PET), functional …

Motor imagery is viewed as a window to cognitive motor processes and particularly to motor
control. Mental simulation theory [Jeannerod, M., 2001. Neural simulation of action: a …

Parkinson's disease causes a characteristic combination of motor symptoms due to
progressive neurodegeneration of dopaminergic neurons in the substantia nigra pars …

Classical accounts of the pathophysiology of Parkinson's disease have emphasized
degeneration of dopaminergic nigrostriatal neurons with consequent dysfunction of cortico …

The motor signs of Parkinson's disease are thought to result in large part from a reduction of
the level of dopamine in the basal ganglia. Over the last few years, many of the functional …

The cerebellum and the basal ganglia are major subcortical nuclei that control multiple
aspects of behavior largely through their interactions with the cerebral cortex. Discrete …