The myelin sheath is a multilayered membrane in the nervous system, which has unique
biochemical properties. Myelin carries a set of specific high‐abundance proteins, the …

The myelin sheath is a multilamellar plasma membrane extension of highly specialized glial
cells laid down in regularly spaced segments along axons. Recent studies indicate that …

The membrane-anchored myelin enzyme 2′, 3′-cyclic nucleotide 3′-phosphodiesterase
(CNPase) was discovered in the early 1960s and has since then troubled scientists with its …

Extracellular adenosine 3′, 5′‐cyclic monophosphate (3′, 5′‐cAMP) is an endogenous
source of localized adenosine production in many organs. Recent studies suggest that …

Myelin ensheathes selected axonal segments within the nervous system, resulting primarily
in nerve impulse acceleration, as well as mechanical and trophic support for neurons. In the …

Abstract 2′, 3′-cyclic nucleotide 3′-phosphodiesterase (CNPase) is an abundant
membrane-associated enzyme within the vertebrate myelin sheath. While the physiological …

Parkinson's disease (PD) is the second most frequent neurodegenerative disorder in the old
population. Among its monogenic variants, a frequent cause is a mutation in the Parkin gene …

Abstract 2′, 3′-cyclic nucleotide 3′-phosphodiesterase (CNPase) is an enzyme highly
abundant in the central nervous system myelin of terrestrial vertebrates. The catalytic …

The roles of calmodulin (CaM), a multifunctional intracellular calcium receptor protein, as
concerns selected morphological and functional characteristics of pure microglial cells …

Calcium as a secondary messenger regulates the phosphorylation of several membrane-
bound proteins in brain and liver mitochondria. Regulation of the activity of different protein …