The halogen bond occurs when there is evidence of a net attractive interaction between an
electrophilic region associated with a halogen atom in a molecular entity and a nucleophilic …

Sigma–hole interactions, in particular halogen bonding (XB) and chalcogen bonding (ChB),
have become indispensable tools in supramolecular chemistry, with wide-ranging …

Halogen bonding, the noncovalent interaction based on electrophilic halogen substituents,
features very interesting properties, as illustrated by numerous applications continuously …

Halogen bonding is a noncovalent interaction similar to hydrogen bonding, which is based
on electrophilic halogen substituents. Hydrogen‐bonding‐based organocatalysis is a well …

Halogen‐and chalcogen‐based σ‐hole interactions have recently received increased
interest in non‐covalent organocatalysis. However, the closely related pnictogen bonds …

Non‐covalent molecular interactions on the basis of halogen and chalcogen bonding
represent a promising, powerful catalytic activation mode. However, these “unusual” non …

We carried out an extensive survey of wave function and DFT methods to test their accuracy
on geometries and dissociation energies of halogen bonds (XB). For that purpose, we built …

A new protocol for photochemical perfluoroalkylation reactions using perfluoroalkyl iodide,
amine additive, and THF solvent is reported. This protocol does not require a photoredox …

Halogen bond has attracted a great deal of attention in the past years for hit-to-lead-to-
candidate optimization aiming at improving drug-target binding affinity. In general, heavy …

In contrast to hydrogen bonding, which is firmly established in organocatalysis, there are still
very few applications of halogen bonding in this field. Herein, we present the first catalytic …