The halogen bond
The halogen bond occurs when there is evidence of a net attractive interaction between an
electrophilic region associated with a halogen atom in a molecular entity and a nucleophilic …
electrophilic region associated with a halogen atom in a molecular entity and a nucleophilic …
Halogen bonding and chalcogen bonding mediated sensing
R Hein, PD Beer - Chemical Science, 2022 - pubs.rsc.org
Sigma–hole interactions, in particular halogen bonding (XB) and chalcogen bonding (ChB),
have become indispensable tools in supramolecular chemistry, with wide-ranging …
have become indispensable tools in supramolecular chemistry, with wide-ranging …
Catalysis of organic reactions through halogen bonding
Halogen bonding, the noncovalent interaction based on electrophilic halogen substituents,
features very interesting properties, as illustrated by numerous applications continuously …
features very interesting properties, as illustrated by numerous applications continuously …
Halogen bonding in organic synthesis and organocatalysis
D Bulfield, SM Huber - Chemistry–A European Journal, 2016 - Wiley Online Library
Halogen bonding is a noncovalent interaction similar to hydrogen bonding, which is based
on electrophilic halogen substituents. Hydrogen‐bonding‐based organocatalysis is a well …
on electrophilic halogen substituents. Hydrogen‐bonding‐based organocatalysis is a well …
Catalysis with pnictogen, chalcogen, and halogen bonds
S Benz, AI Poblador‐Bahamonde… - Angewandte …, 2018 - Wiley Online Library
Halogen‐and chalcogen‐based σ‐hole interactions have recently received increased
interest in non‐covalent organocatalysis. However, the closely related pnictogen bonds …
interest in non‐covalent organocatalysis. However, the closely related pnictogen bonds …
Frontiers in halogen and chalcogen‐bond donor organocatalysis
J Bamberger, F Ostler, OG Mancheño - ChemCatChem, 2019 - Wiley Online Library
Non‐covalent molecular interactions on the basis of halogen and chalcogen bonding
represent a promising, powerful catalytic activation mode. However, these “unusual” non …
represent a promising, powerful catalytic activation mode. However, these “unusual” non …
Halogen bonds: Benchmarks and theoretical analysis
S Kozuch, JML Martin - Journal of chemical theory and …, 2013 - ACS Publications
We carried out an extensive survey of wave function and DFT methods to test their accuracy
on geometries and dissociation energies of halogen bonds (XB). For that purpose, we built …
on geometries and dissociation energies of halogen bonds (XB). For that purpose, we built …
Halogen-bond-promoted photoactivation of perfluoroalkyl iodides: A photochemical protocol for perfluoroalkylation reactions
A new protocol for photochemical perfluoroalkylation reactions using perfluoroalkyl iodide,
amine additive, and THF solvent is reported. This protocol does not require a photoredox …
amine additive, and THF solvent is reported. This protocol does not require a photoredox …
Halogen bond: its role beyond drug–target binding affinity for drug discovery and development
Z Xu, Z Yang, Y Liu, Y Lu, K Chen… - Journal of chemical …, 2014 - ACS Publications
Halogen bond has attracted a great deal of attention in the past years for hit-to-lead-to-
candidate optimization aiming at improving drug-target binding affinity. In general, heavy …
candidate optimization aiming at improving drug-target binding affinity. In general, heavy …
Cationic multidentate halogen-bond donors in halide abstraction organocatalysis: Catalyst optimization by preorganization
SH Jungbauer, SM Huber - Journal of the American Chemical …, 2015 - ACS Publications
In contrast to hydrogen bonding, which is firmly established in organocatalysis, there are still
very few applications of halogen bonding in this field. Herein, we present the first catalytic …
very few applications of halogen bonding in this field. Herein, we present the first catalytic …