Update on the antibiotic resistance crisis
GM Rossolini, F Arena, P Pecile, S Pollini - Current opinion in …, 2014 - Elsevier
Highlights•The antibiotic resistance crisis is jeopardizing feasibility of medical practices.•The
antibiotic resistance crisis is more serious with Gram-negative pathogens.•XDR phenotypes …
antibiotic resistance crisis is more serious with Gram-negative pathogens.•XDR phenotypes …
Carbapenemase-producing Klebsiella pneumoniae, a key pathogen set for global nosocomial dominance
JDD Pitout, P Nordmann, L Poirel - Antimicrobial agents and …, 2015 - Am Soc Microbiol
The management of infections due to Klebsiella pneumoniae has been complicated by the
emergence of antimicrobial resistance, especially to carbapenems. Resistance to …
emergence of antimicrobial resistance, especially to carbapenems. Resistance to …
Treatment Options for Carbapenem-Resistant Enterobacteriaceae Infections
This article provides a comprehensive review of currently available treatment options for
infections due to carbapenem-resistant Enterobacteriaceae (CRE). Antimicrobial resistance …
infections due to carbapenem-resistant Enterobacteriaceae (CRE). Antimicrobial resistance …
Multidrug-resistant and extensively drug-resistant Gram-negative pathogens: current and emerging therapeutic approaches
I Karaiskos, H Giamarellou - Expert opinion on pharmacotherapy, 2014 - Taylor & Francis
Introduction: In the era of multidrug-resistant, extensively drug-resistant (XDR) and even
pandrug-resistant Gram-negative microorganisms, the medical community is facing the …
pandrug-resistant Gram-negative microorganisms, the medical community is facing the …
[HTML][HTML] Treating infections caused by carbapenemase-producing Enterobacteriaceae
Carbapenemase-producing Enterobacteriaceae (CPE) have spread worldwide, causing
serious infections with increasing frequency. CPE are resistant to almost all available …
serious infections with increasing frequency. CPE are resistant to almost all available …
Current Trends in Antimicrobial Resistance of Escherichia coli
Y Paitan - Escherichia coli, a versatile pathogen, 2018 - Springer
Escherichia coli is the most common Gram-negative bacterial pathogen, presenting both a
clinical and an epidemiological challenge. In the last decade, several successful multidrug …
clinical and an epidemiological challenge. In the last decade, several successful multidrug …
Applying pharmacokinetic/pharmacodynamic principles in critically ill patients: optimizing efficacy and reducing resistance development
MH Abdul-Aziz, J Lipman, JW Mouton… - … in respiratory and …, 2015 - thieme-connect.com
The recent surge in multidrug-resistant pathogens combined with the diminishing antibiotic
pipeline has created a growing need to optimize the use of our existing antibiotic …
pipeline has created a growing need to optimize the use of our existing antibiotic …
The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections
T Tängdén, V Ramos Martín, TW Felton… - Intensive care …, 2017 - Springer
Critically ill patients with severe infections are at high risk of suboptimal antimicrobial dosing.
The pharmacokinetics (PK) and pharmacodynamics (PD) of antimicrobials in these patients …
The pharmacokinetics (PK) and pharmacodynamics (PD) of antimicrobials in these patients …
Emerging Gram negative resistance to last-line antimicrobial agents fosfomycin, colistin and ceftazidime-avibactam–epidemiology, laboratory detection and treatment …
ABSTRACT Introduction: Multidrug-resistant (MDR) and extensively-drug-resistant (XDR)
Gram-negative bacteria have emerged as a major threat to human health globally. This has …
Gram-negative bacteria have emerged as a major threat to human health globally. This has …
Risk factors for acute kidney injury (AKI) in patients treated with polymyxin B and influence of AKI on mortality: a multicentre prospective cohort study
MH Rigatto, TF Behle, DR Falci, T Freitas… - Journal of …, 2015 - academic.oup.com
Objectives The objectives of this study were to assess risk factors for acute kidney injury
(AKI) in patients treated with polymyxin B, a last resort antibiotic against Gram-negative …
(AKI) in patients treated with polymyxin B, a last resort antibiotic against Gram-negative …