Altered gene expression is a characteristic feature of many disease states such as
tumorigenesis, and in most cancers, it facilitates cancer cell survival and adaptation …

ABSTRACT RNA-binding proteins (RBPs) are key players in cellular physiology through
posttranscriptional regulation of the expression of target RNA transcripts. By modulating the …

Simple Summary RNA-binding proteins (RBPs) play central roles in regulating
posttranscriptional expression of genes. Many of them are known to be deregulated in a …

The RNA-binding proteins (RBPs) are critical trans factors that associate with specific cis
elements present in mRNAs whose stability and translation are subject to regulation. The …

Protein–RNA interactions have crucial roles in various cellular activities, which, when
dysregulated, can lead to a range of human diseases. The identification of small molecules …

RNA network control is a key aspect of proper cellular homeostasis. In this context, RNA-
binding proteins (RBPs) play a major role as regulators of the RNA life cycle due to their …

Traditionally majority of eukaryotic gene expression is influenced by transcriptional and post-
transcriptional events. Alterations in the expression of proteins that act post-transcriptionally …

The control of eukaryotic gene expression occurs at multiple levels, from transcription to
messenger RNA processing, transport, localization, turnover, and translation. RNA-binding …

Therapy resistance remains a huge challenge for current breast cancer treatments.
Exploring molecular mechanisms of therapy resistance might provide therapeutic targets for …

Patients diagnosed with metastatic breast cancer have a dismal 5-year survival rate of only
24%. The RNA-binding protein Hu antigen R (HuR) is upregulated in breast cancer, and …