Critical illness is a life-changing event for patients and their families. As mortality has
declined, many survivors experience new and persistent impairments in physical …

OBJECTIVE: To develop comprehensive clinical practice guidelines for critically ill infants
and children, with specific attention to seven domains of care including pain …

Background The objective of this study was to describe the case literature of human
coronavirus infections in the nervous system of children, including from SARS-CoV-2, and to …

An estimated 14.1 million patients survive sepsis each year. Many survivors experience poor
long-term outcomes, including new or worsened neuropsychological impairment; physical …

In the last decades, the advancement of knowledge in analgesia and sedation for critically ill
pediatric patients has been conspicuous and relevant. Many recommendations have …

Background Early mobilization of adults receiving intensive care improves health outcomes,
yet little is known about mobilization practices in paediatric intensive care units (PICUs). We …

Objectives: With decreasing mortality in PICUs, a growing number of survivors experience
long-lasting physical impairments. Early physical rehabilitation and mobilization during …

Objectives: A companion article reports the trajectory of long-term mortality and significant
health-related quality of life disability among children encountering septic shock. In this …

Most children are surviving critical illness in highly resourced pediatric intensive care units
(PICUs). However, in research studies, many of these children survive with multi-domain …

Advances in medical and surgical care for children in the pediatric intensive care unit (PICU)
have led to vast reductions in mortality, but survivors often leave with newly acquired or …