Multiple sclerosis (MS) is an autoimmune disease triggered by environmental factors that act
on a genetically susceptible host. It features three clinical stages: a pre-clinical stage …

Background Postoperative nausea and vomiting (PONV) is a common adverse effect of
anaesthesia and surgery. Up to 80% of patients may be affected. These outcomes are a …

Background High-efficacy therapies in multiple sclerosis are traditionally used after
unsuccessful treatment with first-line disease modifying therapies. We hypothesised that …

Background Multiple sclerosis (MS) is an autoimmune, demyelinating disease of the central
nervous system. The treatment of MS has always been a focus of neurological research. To …

Objective To test the hypothesis that immunotherapy prevents long-term disability in
relapsing-remitting multiple sclerosis (MS), we modeled disability outcomes in 14,717 …

Multiple sclerosis (MS) is a common, disabling, putatively autoimmune neurological disease
with worldwide distribution. It typically begins as a relapsing disorder that later evolves to a …

Background and Objective: Altered inflammatory response characterizes chronic
immunemediated inflammatory diseases (IMID) such as rheumatoid arthritis, inflammatory …

Eosinophilic esophagitis (EoE) is a chronic immune-mediated disease of the esophagus
characterized clinically by symptoms related to esophageal dysfunction and histologically by …

1Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute
of Neurology, London, UK; 2National Hospital for Neurology and Neurosurgery, Queen …

Aim: To compare the efficacy of ofatumumab to other disease-modifying therapies (DMTs)
for relapsing multiple sclerosis (RMS). Materials & methods: A network meta-analysis was …