Genetic variants and altered expression of SERPINF1 confer disease susceptibility in patients with otosclerosis
Otosclerosis (OTSC) is a focal and diffuse bone disorder of the human middle ear
characterized by abnormal bone growth and deposition at the stapes' footplate. This hinders …
characterized by abnormal bone growth and deposition at the stapes' footplate. This hinders …
Targeted resequencing of otosclerosis patients from different populations replicates results from a previous genome-wide association study
LJM Tavernier, T Vanpoucke, I Schrauwen… - Journal of Clinical …, 2022 - mdpi.com
Otosclerosis is one of the most common causes of hearing loss in young adults. It has a
prevalence of 0.3–0.4% in the European population. Clinical symptoms usually occur …
prevalence of 0.3–0.4% in the European population. Clinical symptoms usually occur …
Identification of hub genes and biological process analysis of otosclerosis patients based on WGCNA analysis
W Wang, D Zhang, M Lei, Y Wang, P Zeng, C Zou… - 2023 - researchsquare.com
Background: Otosclerosis is a primary bone disease caused by the bone labyrinth,
resorption, and abnormal bone deposition. According to current research, it is a complex …
resorption, and abnormal bone deposition. According to current research, it is a complex …