Idiopathic pulmonary fibrosis (IPF) is a progressive pulmonary interstitial inflammatory
disease of unknown etiology, and is also a sequela in severe patients with the Coronavirus …

Celastrol, triptolide and triptonide are the most significant active ingredients of Tripterygium
wilfordii Hook F (TWHF). In 2007, the 'Cell'journal ranked celastrol, triptolide, artemisinin …

Celastrol, a natural bioactive ingredient derived from Tripterygium wilfordii Hook F, exhibits
significant broad-spectrum anticancer activities for the treatment of a variety of cancers …

Epithelial-to-mesenchymal transition (EMT) is a self-regulated physiological process
required for tissue repair that, in non-controled conditions may lead to fibrosis …

Ethnopharmacological relevance Interstitial lung disease (ILD) is a chronic lung dysfunction
disease with a poor prognosis and poor recovery. The clinically used therapeutic drugs …

Introduction Pulmonary fibrosis (PF) is characterized by an increase in collagen synthesis
and deposition of extracellular matrix. Several factors, including transforming growth factor …

Pulmonary fibrosis (PF) is a disease-refractive lung condition with an increased rate of
mortality. The potential factors causing PF include viral infections, radiation exposure, and …

Pulmonary fibrosis is an incurable end-stage lung disease and remains a global public
health problem. Although there have been some breakthroughs in understanding the …

Platinum-based drugs (PBDs), including cisplatin, carboplatin, and oxaliplatin, have been
widely used in clinical practice as mainstay treatments for various types of cancer. Although …

Evidence is mounting that abnormal vascular remodeling leads to many cardiovascular
diseases (CVDs). This suggests that vascular remodeling can be a crucial target for the …