Mitochondrial DNA (mtDNA) variation in common diseases has been underexplored, partly
due to a lack of genotype calling and quality-control procedures. Developing an at-scale …

Previous studies have suggested that certain variants in immune-related genes may
participate in the pathogenesis of multiple sclerosis (MS), including rs17824933 in the CD6 …

Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system with
genetics and environmental determinants. Studies focused on the neurogenetics of MS …

Multiple sclerosis (MS) is a chronic disease of the central nervous system characterized by
the autoimmune inflammation, demyelination, and neurodegeneration. This complex …

To evaluate the influence of mitochondrial DNA haplogroups on the risk of knee OA in terms
of their interaction with obesity, in a population from Mexico. Samples were obtained from …

Previous studies have suggested that mitochondrial DNA (mtDNA) variants are associated
with multiple sclerosis (MS), a complex neurodegenerative immune-mediated disease of the …

Osteoarthritis (OA) is the most prevalent chronic joint disease, and we actually know that the
activation of maladaptive responses to injury, including pro-inflammatory pathways, leads to …

Objective To investigate genetic interactions between mitochondrial deoxyribonucleic acid
(mtDNA) haplogroups and nuclear single nucleotide polymorphisms (nSNPs) to analyze …

Mitochondrial DNA (mtDNA) has been an invaluable source of genetic information for
understanding the long-term migration history, genetic diversity, and demographic structure …

Multiple sclerosis (MS) is a chronic autoimmune disease, in the pathogenesis of which the
concurrence of demyelination of central nervous system (CNS) axons and …