Photoclick chemistry: a bright idea

BD Fairbanks, LJ Macdougall, S Mavila, J Sinha… - Chemical …, 2021 - ACS Publications
At its basic conceptualization, photoclick chemistry embodies a collection of click reactions
that are performed via the application of light. The emergence of this concept has had …

Engineered Synthetic Matrices for Human Intestinal Organoid Culture and Therapeutic Delivery

A Mulero‐Russe, AJ García - Advanced Materials, 2024 - Wiley Online Library
Human intestinal organoids (HIOs) derived from pluripotent stem cells or adult stem cell
biopsies represent a powerful platform to study human development, drug testing, and …

Ellagic acid–cyclodextrin inclusion complex-loaded thiol–ene hydrogel with antioxidant, antibacterial, and anti-inflammatory properties for wound healing

T Zhang, L Guo, R Li, J Shao, L Lu… - … Applied Materials & …, 2023 - ACS Publications
Hydrogel dressings not only have basic functions such as swelling, water retention, gas
permeability, and good biocompatibility but also can be endowed with advanced functions …

Hydrolytic hydrogels tune mesenchymal stem cell persistence and immunomodulation for enhanced diabetic cutaneous wound healing

KE Martin, MD Hunckler, E Chee, JD Caplin, GF Barber… - Biomaterials, 2023 - Elsevier
Diabetes is associated with an altered global inflammatory state with impaired wound
healing. Mesenchymal stem/stromal cells (MSC) are being explored for treatment of diabetic …

Facile photopatterning of perfusable microchannels in synthetic hydrogels to recreate microphysiological environments

A Mora‐Boza, A Mulero‐Russe, ND Caprio… - Advanced …, 2023 - Wiley Online Library
The fabrication of perfusable hydrogels is crucial for recreating in vitro microphysiological
environments. Existing strategies to fabricate complex microchannels in hydrogels involve …

4D printing of extrudable and degradable poly (ethylene glycol) microgel scaffolds for multidimensional cell culture

CE Miksch, NP Skillin, BE Kirkpatrick, GK Hach… - Small, 2022 - Wiley Online Library
Granular synthetic hydrogels are useful bioinks for their compatibility with a variety of
chemistries, affording printable, stimuli‐responsive scaffolds with programmable structure …

Decoupled pH‐and thermo‐responsive injectable chitosan/PNIPAM hydrogel via thiol‐ene click chemistry for potential applications in tissue engineering

H Ding, B Li, Z Liu, G Liu, S Pu, Y Feng… - Advanced …, 2020 - Wiley Online Library
Stimuli‐responsive chitosan (CS) hydrogels exhibit great potential for drug delivery and
tissue engineering; however, the structure of these stimuli‐responsive CS hydrogels, such …

[HTML][HTML] Design and characterization of matrix metalloproteinase-responsive hydrogels for the treatment of inflammatory skin diseases

HK Noddeland, M Lind, LB Jensen, K Petersson… - Acta Biomaterialia, 2023 - Elsevier
Enzyme-responsive hydrogels, formed by step growth photopolymerization of biscysteine
peptide linkers with alkene functionalized polyethylene glycol, provide interesting …

Hydrolytically degradable microgels with tunable mechanical properties modulate the host immune response

MM Coronel, KE Martin, MD Hunckler, P Kalelkar… - Small, 2022 - Wiley Online Library
Hydrogel microparticles (microgels) are an attractive approach for therapeutic delivery
because of their modularity, injectability, and enhanced integration with the host tissue …

Rapid and Facile Light‐Based Approach to Fabricate Protease‐Degradable Poly (ethylene glycol)− norbornene Microgels for Cell Encapsulation

A Mora‐Boza, SG Ghebrezadik… - Advanced …, 2023 - Wiley Online Library
Thiol‐norbornene photoclickable poly (ethylene glycol)(PEG)‐based (PEG‐NB) hydrogels
are attractive biomaterials for cell encapsulation, drug delivery, and regenerative medicine …