Fibrosis results from defective wound healing processes often seen after chronic injury
and/or inflammation in a range of organs. Progressive fibrotic events may lead to permanent …

Pulmonary fibrosis is characterised by excessive scarring in the lung which leads to
compromised lung function, serious breathing problems and in some diseases, death. It …

The hippo signaling pathway is a highly conserved evolutionary signaling pathway that
plays an important role in regulating cell proliferation, organ size, tissue development, and …

The ability of cells to sense and respond to changes in mechanical environment is vital in
conditions of organ injury when the architecture of normal tissues is disturbed or lost. Among …

Simple Summary Although great breakthroughs have been made in cancer treatment
following the development of targeted therapy and immune therapy, resistance against anti …

The yes-associated protein (YAP) and the transcriptional coactivator with PDZ-binding motif
(TAZ) are transcriptional coactivators, members of the Hippo signaling pathway, which play …

Excessive scar formation caused by cutaneous injury leads to pruritus, pain, contracture,
dyskinesia, and unpleasant appearance. Functional wound dressings are designed to …

In recent years, research focused on the multifaceted landscape and functions of cancer-
associated fibroblasts (CAFs) aimed to reveal their heterogeneity and identify commonalities …

Metabolic changes occur in all forms of disease but their impact on fibrosis is a relatively
recent area of interest. This review provides an overview of the major metabolic pathways …

Idiopathic pulmonary fibrosis (IPF) is a chronic irreversible interstitial lung disease
characterized by a progressive decline in lung function. The etiology of IPF is unknown …