The enteric nervous system in gastrointestinal disease etiology
AM Holland, AC Bon-Frauches, D Keszthelyi… - Cellular and Molecular …, 2021 - Springer
A highly conserved but convoluted network of neurons and glial cells, the enteric nervous
system (ENS), is positioned along the wall of the gut to coordinate digestive processes and …
system (ENS), is positioned along the wall of the gut to coordinate digestive processes and …
Impact of genes and the environment on the pathogenesis and disease course of inflammatory bowel disease
Crohn's disease and ulcerative colitis constitute two major subgroups of inflammatory bowel
diseases (IBD), a group of complex polygenic diseases characterized by chronic and …
diseases (IBD), a group of complex polygenic diseases characterized by chronic and …
The infant gut virome is associated with preschool asthma risk independently of bacteria
Bacteriophage (also known as phage) communities that inhabit the gut have a major effect
on the structure and functioning of bacterial populations, but their roles and association with …
on the structure and functioning of bacterial populations, but their roles and association with …
Fibre intake and the development of inflammatory bowel disease: A European prospective multi-centre cohort study (EPIC-IBD)
V Andersen, S Chan, R Luben, KT Khaw… - Journal of Crohn's …, 2018 - academic.oup.com
Abstract Background and Aims Population-based prospective cohort studies investigating
fibre intake and development of inflammatory bowel disease are lacking. Our aim was to …
fibre intake and development of inflammatory bowel disease are lacking. Our aim was to …
Polymorphisms in the NF kB, TNF‐alpha, IL‐1beta, and IL‐18 pathways are associated with response to anti‐TNF therapy in Danish patients with inflammatory bowel …
S Bank, M Julsgaard, OK Abed… - Alimentary …, 2019 - Wiley Online Library
Background Anti‐tumor necrosis factor‐α (TNF‐α) is used for the treatment of severe cases
of IBD, including Crohn's disease (CD) and ulcerative colitis (UC). However, one‐third of the …
of IBD, including Crohn's disease (CD) and ulcerative colitis (UC). However, one‐third of the …
Communication between the microbiota and mammalian immunity
Mammalian immune systems evolved within a diverse world dominated by microbes,
making interactions between these two life-forms inevitable. Adaptive immunity protects …
making interactions between these two life-forms inevitable. Adaptive immunity protects …
Genetically determined high activities of the TNF-alpha, IL23/IL17, and NFkB pathways were associated with increased risk of ankylosing spondylitis
J Sode, S Bank, U Vogel, PS Andersen… - BMC Medical …, 2018 - Springer
Background Ankylosing spondylitis (AS) results from the combined effects of susceptibility
genes and environmental factors. Polymorphisms in genes regulating inflammation may …
genes and environmental factors. Polymorphisms in genes regulating inflammation may …
5-Aminosalicylic acid, a specific drug for ulcerative colitis
Ø Hauso, TC Martinsen, H Waldum - Scandinavian journal of …, 2015 - Taylor & Francis
Objective. The etiology of the inflammatory bowel diseases is unknown, although genetic
factors play a role, and tobacco smoking has opposite effect on the two entities. Inflammation …
factors play a role, and tobacco smoking has opposite effect on the two entities. Inflammation …
Associations between functional polymorphisms and response to biological treatment in Danish patients with psoriasis
Biological agents including anti-tumor necrosis factor (anti-TNF; adalimumab, infliximab,
etanercept) and anti-interleukin-12/13 (IL12/23; ustekinumab) are essential for treatment of …
etanercept) and anti-interleukin-12/13 (IL12/23; ustekinumab) are essential for treatment of …
Age‐related macular degeneration: insights into inflammatory genes
R Cascella, M Ragazzo, C Strafella… - Journal of …, 2014 - Wiley Online Library
Age‐related macular degeneration (AMD) is a progressive neurodegenerative disease that
affects approximately 8.7% of elderly people worldwide (> 55 years old). AMD is …
affects approximately 8.7% of elderly people worldwide (> 55 years old). AMD is …