Maternal metabolism influences neural tube closure

RA Keuls, RH Finnell, RJ Parchem - Trends in Endocrinology & Metabolism, 2023 - cell.com
Changes in maternal nutrient availability due to diet or disease significantly increase the risk
of neural tube defects (NTDs). Because the incidence of metabolic disease continues to rise …

How food matrices modulate folate bioaccessibility: A comprehensive overview of recent advances and challenges

F Liu, M Edelmann, V Piironen, Y Li… - … Reviews in Food …, 2024 - Wiley Online Library
The incomplete absorption of dietary folate makes it crucial to understand how food matrices
affect folate bioaccessibility. Bioavailability encompasses bioaccessibility, which depicts the …

[HTML][HTML] Pregnancy, folic acid, and antiseizure medication

MH Bjørk, H Vegrim, S Alvestad, AL Bjørke-Monsen… - Clinical …, 2023 - Springer
Background Although some antiseizure medications (ASMs) are teratogenic, most people
with epilepsy need treatment in pregnancy. The risk of ASM fetotoxicity may be mitigated …

Interactions of arsenic exposure, arsenic metabolism with red blood cell folate on the risk of hypertension: NHANES 2007–2016

Y Gong, Y Li, X Zhang, Y Ma, Y Wu, X Zhi - Food and Chemical Toxicology, 2023 - Elsevier
Purpose Arsenic exposure was associated with hypertension, and arsenic metabolism might
be influenced by folate concentrations. Thus, this study aimed to explore the interaction …

[HTML][HTML] Advances in Folic Acid Biosensors and Their Significance in Maternal, Perinatal, and Paediatric Preventive Medicine

Y Movendane, MG Sipalo, LCZ Chan - Biosensors, 2023 - mdpi.com
Auxotrophic primates like human beings rely on exogenous dietary vitamin B9
supplementation to meet their metabolic demands. Folates play a crucial role in nucleotide …

[HTML][HTML] Hyperhomocysteinemia in hypofertile male patients can be alleviated by supplementation with 5MTHF associated with one carbon cycle support

A Clement, E Amar, P Clement, É Sedbon… - … in Reproductive Health, 2023 - frontiersin.org
Introduction Homocysteine (Hcy) is a cellular poison, side product of the hydrolysis of S-
Adenosyl Homocysteine, produced after the universal methylation effector S …

[HTML][HTML] Reanalysis of Trio Whole-Genome Sequencing Data Doubles the Yield in Autism Spectrum Disorder: De Novo Variants Present in Half

O Bar, E Vahey, M Mintz, RE Frye… - International Journal of …, 2024 - mdpi.com
Autism spectrum disorder (ASD) is a common condition with lifelong implications. The last
decade has seen dramatic improvements in DNA sequencing and related bioinformatics …

Quaternary ammonium salt modified magnetic solid-phase extraction beads with different chain lengths for efficient enrichment of five types of folates in blood

H Tang, L He, Z Zhou, W Cheng, Z Liu, X Yan… - Separation and …, 2024 - Elsevier
This study used quaternary ammonium functionalized magnetic beads (QAMBs) as
magnetic solid-phase extraction (MSPE) sorbents and liquid chromatography-tandem mass …

[HTML][HTML] Optimal folic acid dosage in lowering homocysteine: Precision Folic Acid Trial to lower homocysteine (PFAT-Hcy)

X Huang, H Bao, C Ding, J Li, T Cao, L Liu… - European Journal of …, 2024 - Springer
Background While folic acid (FA) is widely used to treat elevated total homocysteine (tHcy),
promoting vascular health by reducing vascular oxidative stress and modulating endothelial …

[HTML][HTML] Health effects and pathophysiological mechanisms of one-carbon metabolism nutrients intake throughout the life cycle

J Liu, Y Lei, L Wang, C Guo - Frontiers in Nutrition, 2023 - frontiersin.org
The early-life nutritional environment, especially periconceptional nutrition, plays a critical
role in shaping adverse health outcomes. These can encompass congenital malformations …