[HTML][HTML] BDNF signaling in context: From synaptic regulation to psychiatric disorders

CS Wang, ET Kavalali, LM Monteggia - Cell, 2022 - cell.com
Brain-derived neurotrophic factor (BDNF) is a neuropeptide that plays numerous important
roles in synaptic development and plasticity. While its importance in fundamental physiology …

[HTML][HTML] Brain-derived neurotrophic factor in Alzheimer's disease and its pharmaceutical potential

L Gao, Y Zhang, K Sterling, W Song - Translational neurodegeneration, 2022 - Springer
Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …

[HTML][HTML] Neurotrophic factor BDNF, physiological functions and therapeutic potential in depression, neurodegeneration and brain cancer

L Colucci-D'Amato, L Speranza, F Volpicelli - International journal of …, 2020 - mdpi.com
Brain-derived neurotrophic factor (BDNF) is one of the most distributed and extensively
studied neurotrophins in the mammalian brain. BDNF signals through the tropomycin …

[HTML][HTML] Brain-derived neurotrophic factor in brain disorders: focus on neuroinflammation

B Lima Giacobbo, J Doorduin, HC Klein… - Molecular …, 2019 - Springer
Brain-derived neurotrophic factor (BDNF) is one of the most studied neurotrophins in the
healthy and diseased brain. As a result, there is a large body of evidence that associates …

[HTML][HTML] Recent advances on the role of brain-derived neurotrophic factor (BDNF) in neurodegenerative diseases

KF Azman, R Zakaria - International journal of molecular sciences, 2022 - mdpi.com
Neurotrophins, such as brain-derived neurotrophic factor (BDNF), are essential for neuronal
survival and growth. The signaling cascades initiated by BDNF and its receptor are the key …

[HTML][HTML] The role of BDNF on neural plasticity in depression

T Yang, Z Nie, H Shu, Y Kuang, X Chen… - Frontiers in cellular …, 2020 - frontiersin.org
Using behavioral, pharmacological, and molecular methods, lots of studies reveal that
depression is closely related to the abnormal neural plasticity processes occurring in the …

[HTML][HTML] BDNF: a key factor with multipotent impact on brain signaling and synaptic plasticity

P Kowiański, G Lietzau, E Czuba, M Waśkow… - Cellular and molecular …, 2018 - Springer
Brain-derived neurotrophic factor (BDNF) is one of the most widely distributed and
extensively studied neurotrophins in the mammalian brain. Among its prominent functions …

BDNF and hippocampal synaptic plasticity

G Leal, CR Bramham, CB Duarte - Vitamins and hormones, 2017 - Elsevier
Brain-derived neurotrophic factor (BDNF) belongs to a family of small secreted proteins that
also include nerve growth factor, neurotrophin 3, and neurotrophin 4. BDNF stands out …

[HTML][HTML] Axonal transport: cargo-specific mechanisms of motility and regulation

S Maday, AE Twelvetrees, AJ Moughamian… - Neuron, 2014 - cell.com
Axonal transport is essential for neuronal function, and many neurodevelopmental and
neurodegenerative diseases result from mutations in the axonal transport machinery …

[HTML][HTML] Neurobiology of local and intercellular BDNF signaling

M Sasi, B Vignoli, M Canossa, R Blum - Pflügers Archiv-European Journal …, 2017 - Springer
Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family of secreted
proteins. Signaling cascades induced by BDNF and its receptor, the receptor tyrosine kinase …