The endocannabinoid system (ECS) is a widespread neuromodulatory network involved in
the developing central nervous system as well as playing a major role in tuning many …

Rationale Cannabidiol (CBD) products lacking regulatory approval are being used to self-
treat a myriad of conditions and for their unsubstantiated health benefits. The scientific …

Background: Cannabidiol is being pursued as a therapeutic treatment for multiple
conditions, usually by oral delivery. Animal studies suggest oral bioavailability is low, but …

As countries adopt more permissive cannabis policies, it is increasingly important to identify
strategies that can reduce the harmful effects of cannabis use. This study aimed to determine …

In an increasing number of states and countries, cannabis now stands poised to join alcohol
and tobacco as a legal drug. Quantifying the relative adverse and beneficial effects of …

Importance Controlled clinical laboratory studies have shown that cannabidiol (CBD) can
sometimes attenuate or exacerbate the effects ofΔ9-tetrahydrocannabinol (Δ9-THC). No …

The recent liberalisation of cannabis regulation has increased public and scientific debate
about its potential benefits and risks. A key focus has been the extent to which cannabidiol …

Laws regulating cannabis have changed radically in the US and abroad. Historically, users
smoked dried cannabis flowers that contained Δ9-tetrahydrocannabinol (THC), the primary …

Considering data from in vitro and in vivo studies, cannabidiol (CBD) seems to be a
promising candidate for the treatment of both somatic and psychiatric disorders. The aim of …

The plant Cannabis sativa, commonly called cannabis or marijuana, has been used for its
psychotropic and mind-altering side effects for millennia. There has been growing attention …