During the last years, accumulating evidence has suggested that the gut microbiota plays a
key role in the pathogenesis of neurodevelopmental and neurodegenerative diseases via …

Tissue engineering is an interdisciplinary field that combines stem cells and matrices to form
functional constructs that can be used to repair damaged tissues or regenerate whole …

Gut microbial products direct growth, differentiation, and development in animal hosts.
However, we lack system-wide understanding of cell-specific responses to the microbiome …

Epidemiological and preclinical studies have indicated a factual association between gut
microbiota dysbiosis and high incidence of colitis. Dietary polysaccharides can specifically …

Animal development proceeds in the presence of intimate microbial associations, but the
extent to which different host cells across the body respond to resident microbes remains to …

The intestinal epithelium is a complex tissue monolayer composed of regionally and
functionally specialized intestinal epithelial cells. Given epithelial exposure to harsh and …

Background & Aims The intestine constantly interprets and adapts to complex combinations
of dietary and microbial stimuli. However, the transcriptional strategies by which the …

Resembling the development of cancer by multistep carcinogenesis, the evolution towards
metastasis involves several passages, from local invasion and intravasation, encompassing …

Control of gut microbes is crucial for not only local defense in the intestine but also proper
systemic immune responses. Although intestinal epithelial cells (IECs) play important roles …

A major cause of intestinal failure (IF) is intestinal epithelium necrosis and massive loss of
enterocytes, especially in the jejunum, the major intestinal segment in charge of nutrient …