The aim of this article is to survey the accessible writing on the pathogenetic systems
engaged with the relationship between oral malignancy and periodontitis. Gingival tissue …

Proteases are signaling molecules that specifically control cellular functions by cleaving
protease-activated receptors (PARs). The four known PARs are members of the large family …

Ulcerative colitis (UC) is driven by disruptions in host–microbiota homoeostasis, but current
treatments exclusively target host inflammatory pathways. To understand how host …

The oral microbiota plays an important role in the human microbiome and human health,
and imbalances between microbes and their hosts can lead to oral and systemic diseases …

Background & Aims Altered gut microbiota composition and function have been associated
with inflammatory bowel diseases, including ulcerative colitis (UC), but the causality and …

The way sporadic Parkinson's disease (PD) is perceived has undergone drastic changes in
recent decades. For a long time, PD was considered a brain disease characterized by motor …

Worldwide, millions of individuals have been affected by the prevailing SARS-CoV-2.
Therefore, a robust immune system remains indispensable, as an immunocompromised …

Background & Aims The gut microbiome has been suggested to play a role in gut barrier
hemostasis, but data are scarce and limited to animal studies. We therefore aimed to assess …

Rheumatoid arthritis (RA) is a progressive inflammatory disorder characterized by swollen
joints, discomfort, tightness, bone degeneration and frailty. Genetic, agamogenetic and sex …

Preterm births are a global health priority that affects 15 million babies every year worldwide.
There are no effective prognostic and therapeutic strategies relating to preterm delivery, but …