Benzodiazepines in Alzheimer's disease: beneficial or detrimental effects

HM Al-Kuraishy, AI Al-Gareeb, HM Saad… - …, 2023 - Springer
Dementia is considered a clinical syndrome characterized by cognitive dysfunction and
memory loss. Alzheimer's disease (AD) is the most common type of dementia. AD is linked …

Insights on benzodiazepines' potential in Alzheimer's disease

HM Al-Kuraishy, AI Al-Gareeb, AA Alsayegh… - Life Sciences, 2023 - Elsevier
Alzheimer's disease (AD) is the most frequent type of dementia characterized by the
deposition of amyloid beta (Aβ) plaque and tau-neurofibrillary tangles (TNTs) in the brain …

Adverse drug reactions in SARS-CoV-2 hospitalised patients: a case-series with a focus on drug–drug interactions

G Crescioli, V Brilli, C Lanzi, A Burgalassi, A Ieri… - Internal and Emergency …, 2021 - Springer
Due to the need of early and emergency effective treatments for COVID-19, less attention
may have been paid to their safety during the global emergency. In addition, characteristics …

Suspected adverse reactions to medications and food supplements containing Serenoa repens: A worldwide analysis of pharmacovigilance and phytovigilance …

G Crescioli, V Maggini, E Raschi… - Phytotherapy …, 2023 - Wiley Online Library
The safety of Serenoa repens (SR)‐containing products was evaluated conducting a
retrospective worldwide analysis of pharmaco‐and phytovigilance report forms of suspected …

Drug-related hypersensitivity reactions leading to emergency department: original data and systematic review

S Pagani, N Lombardi, G Crescioli, VG Vighi… - Journal of Clinical …, 2022 - mdpi.com
The aim of the present study is to describe pharmacological characteristics of drug-related
allergies and anaphylaxis leading to the emergency department (ED). An 8-year post hoc …

Structural and functional damage to the retina and skeletal muscle in Xenopus laevis embryos exposed to the commonly used psychotropic benzodiazepine …

C Fogliano, R Carotenuto, G Rusciano, A Sasso… - Environmental …, 2023 - Elsevier
Benzodiazepines, psychotropic drugs, are among the most frequently found
pharmaceuticals in aquatic matrices. An increasing number of studies are reporting their …

Risk of hospitalization associated with cardiovascular medications in the elderly Italian population: A nationwide multicenter study in emergency departments

G Crescioli, A Bettiol, R Bonaiuti, M Tuccori… - Frontiers in …, 2021 - frontiersin.org
Background: There is a significant gap in knowledge addressing cardiovascular (CV)
medications safety in elderly. In this context, our purposes were to define clinical and …

Language‐agnostic pharmacovigilant text mining to elicit side effects from clinical notes and hospital medication records

BS Kaas‐Hansen, D Placido… - Basic & clinical …, 2022 - Wiley Online Library
We sought to craft a drug safety signalling pipeline associating latent information in clinical
free text with exposures to single drugs and drug pairs. Data arose from 12 secondary and …

Risk of hospitalization for adverse drug events in women and men: A post hoc analysis of an active pharmacovigilance study in Italian emergency departments

G Crescioli, E Boscia, A Bettiol, S Pagani, G Spada… - Pharmaceuticals, 2021 - mdpi.com
This post hoc analysis of an Italian active pharmacovigilance study describes
pharmacological differences of ADEs leading to emergency department (ED) visits and …

Phenobarbital use in benzodiazepine and z-drug detoxification: A single-centre 15-year observational retrospective study in clinical practice

S Sartori, G Crescioli, V Brilli, S Traversoni… - Internal and Emergency …, 2022 - Springer
Given the increase in benzodiazepine (BZD) and Z-drug (ZD) use disorder, this study
described the use of phenobarbital (PHB) as detoxification in clinical practice. A 15-year …