Role of the nervous system in cancer metastasis

N Kuol, L Stojanovska, V Apostolopoulos… - Journal of Experimental & …, 2018 - Springer
Cancer remains as one of the leading cause of death worldwide. The development of cancer
involves an intricate process, wherein many identified and unidentified factors play a role …

[HTML][HTML] Prognostic impact of perineural invasion in oral cancer: a systematic review

DMVO Quintana, RA Dedivitis… - Acta …, 2022 - ncbi.nlm.nih.gov
Methods A literature review was carried out, searching the MedLine databases via Pubmed,
Scielo, Lilacs, Cochrane and Websco. Results A total of 56 studies were included. The …

IFIT1 and IFIT3 promote oral squamous cell carcinoma metastasis and contribute to the anti-tumor effect of gefitinib via enhancing p-EGFR recycling

VK Pidugu, MM Wu, AH Yen, HB Pidugu, KW Chang… - Oncogene, 2019 - nature.com
IFIT1 and IFIT3 are abundant products of interferon-stimulating genes. While the importance
of IFIT1 and IFIT3 in the prognosis of cancer has been reported, the molecular basis of IFIT1 …

Clinico-pathological prognosticators in oral squamous cell carcinoma: An update

B Majumdar, S Patil, SC Sarode… - … Research in Oral …, 2017 - journals.sagepub.com
Despite diagnostic and therapeutic advancements, mortality and morbidity rates in the
patients diagnosed with oral cancer remain static. Hence, an understanding of the factors …

The connection between MicroRNAs and oral cancer pathogenesis: emerging biomarkers in oral cancer management

C Osan, S Chira, AM Nutu, C Braicu, M Baciut… - Genes, 2021 - mdpi.com
Oral cancer is a common human malignancy that still maintains an elevated mortality rate
despite scientific progress. Tumorigenesis is driven by altered gene expression patterns of …

A proposal to revise the histopathologic grading system of early oral tongue cancer incorporating tumor budding

A Elseragy, T Salo, RD Coletta… - The American journal …, 2019 - journals.lww.com
Abstract The World Health Organization (WHO) grading system has a low prognostic value
for early-stage oral tongue squamous cell carcinoma; greater prognostic power has been …

Prognostic impact of perineural invasion in early stage oral tongue squamous cell carcinoma: results from a prospective randomized trial

X Yang, X Tian, K Wu, W Liu, S Li, Z Zhang, C Zhang - Surgical oncology, 2018 - Elsevier
Background Although perineural invasion (PNI) has been recognized as a poor prognostic
factor for oral cancer, few studies have focused on tongue squamous cell carcinoma …

[HTML][HTML] A histopathological evaluation and potential prognostic implications of oral squamous cell carcinoma with adverse features

WC Chang, CF Chang, YH Li, CY Yang, RY Su, CK Lin… - Oral Oncology, 2019 - Elsevier
Objectives This study aimed to evaluate the adverse clinicopathologic features of oral
squamous cell carcinoma (OSCC), including margin status, depth of invasion …

Oral squamous cell carcinoma: Diagnosis and treatment planning

V Deshmukh, K Shekar - Oral and maxillofacial surgery for the clinician, 2021 - Springer
Abstract The incidence of Oral Squamous Cell Carcinoma (OSCC) is on the rise. Association
with tobacco and alcohol is well established. Transformation rates in premalignant lesions …

Perineural invasion is a significant prognostic factor in oral squamous cell carcinoma: a systematic review and meta-analysis

N Binmadi, M Alsharif, S Almazrooa, S Aljohani… - Diagnostics, 2023 - mdpi.com
(1) Objectives: This systematic review and meta-analysis aimed to summarize current
evidence regarding the prognostic role of perineural invasion (PNI) in patients with oral …