Skeletal muscle: A review of molecular structure and function, in health and disease
K Mukund, S Subramaniam - Wiley Interdisciplinary Reviews …, 2020 - Wiley Online Library
Decades of research in skeletal muscle physiology have provided multiscale insights into
the structural and functional complexity of this important anatomical tissue, designed to …
the structural and functional complexity of this important anatomical tissue, designed to …
Role of inactivity in chronic diseases: evolutionary insight and pathophysiological mechanisms
FW Booth, CK Roberts, JP Thyfault… - Physiological …, 2017 - journals.physiology.org
This review proposes that physical inactivity could be considered a behavior selected by
evolution for resting, and also selected to be reinforcing in life-threatening situations in …
evolution for resting, and also selected to be reinforcing in life-threatening situations in …
[HTML][HTML] Sarcopenia in the older adult with cancer
The term sarcopenia, derived from the Greek words sarx for flesh and penia for loss, was first
introduced by Rosenberg 1 in 1989 to describe the loss of muscle mass that accompanies …
introduced by Rosenberg 1 in 1989 to describe the loss of muscle mass that accompanies …
Pathophysiological mechanisms leading to muscle loss in chronic kidney disease
Loss of muscle proteins is a deleterious consequence of chronic kidney disease (CKD) that
causes a decrease in muscle strength and function, and can lead to a reduction in quality of …
causes a decrease in muscle strength and function, and can lead to a reduction in quality of …
The connection between the dynamic remodeling of the mitochondrial network and the regulation of muscle mass
V Romanello, M Sandri - Cellular and Molecular Life Sciences, 2021 - Springer
The dynamic coordination of processes controlling the quality of the mitochondrial network is
crucial to maintain the function of mitochondria in skeletal muscle. Changes of mitochondrial …
crucial to maintain the function of mitochondria in skeletal muscle. Changes of mitochondrial …
Vitamin D and sarcopenia: potential of vitamin D supplementation in sarcopenia prevention and treatment
R Uchitomi, M Oyabu, Y Kamei - Nutrients, 2020 - mdpi.com
Skeletal muscle, the largest organ in the human body, accounting for approximately 40% of
body weight, plays important roles in exercise and energy expenditure. In the elderly, there …
body weight, plays important roles in exercise and energy expenditure. In the elderly, there …
Muscle wasting in disease: molecular mechanisms and promising therapies
S Cohen, JA Nathan, AL Goldberg - Nature reviews Drug discovery, 2015 - nature.com
Atrophy occurs in specific muscles with inactivity (for example, during plaster cast
immobilization) or denervation (for example, in patients with spinal cord injuries). Muscle …
immobilization) or denervation (for example, in patients with spinal cord injuries). Muscle …
Rheumatoid sarcopenia: loss of skeletal muscle strength and mass in rheumatoid arthritis
Sarcopenia, a disorder that involves the generalized loss of skeletal muscle strength and
mass, was formally recognized as a disease by its inclusion in the International …
mass, was formally recognized as a disease by its inclusion in the International …
Skeletal muscle atrophy and the E3 ubiquitin ligases MuRF1 and MAFbx/atrogin-1
Muscle RING finger 1 (MuRF1) and muscle atrophy F-box (MAFbx)/atrogin-1 were identified
more than 10 years ago as two muscle-specific E3 ubiquitin ligases that are increased …
more than 10 years ago as two muscle-specific E3 ubiquitin ligases that are increased …
Regulation of autophagy and the ubiquitin–proteasome system by the FoxO transcriptional network during muscle atrophy
G Milan, V Romanello, F Pescatore, A Armani… - Nature …, 2015 - nature.com
Stresses like low nutrients, systemic inflammation, cancer or infections provoke a catabolic
state characterized by enhanced muscle proteolysis and amino acid release to sustain liver …
state characterized by enhanced muscle proteolysis and amino acid release to sustain liver …