Machine learning in drug discovery: a review

S Dara, S Dhamercherla, SS Jadav, CHM Babu… - Artificial intelligence …, 2022 - Springer
This review provides the feasible literature on drug discovery through ML tools and
techniques that are enforced in every phase of drug development to accelerate the research …

Harnessing multimodal data integration to advance precision oncology

KM Boehm, P Khosravi, R Vanguri, J Gao… - Nature Reviews …, 2022 - nature.com
Advances in quantitative biomarker development have accelerated new forms of data-driven
insights for patients with cancer. However, most approaches are limited to a single mode of …

A review of deep learning in medical imaging: Imaging traits, technology trends, case studies with progress highlights, and future promises

SK Zhou, H Greenspan, C Davatzikos… - Proceedings of the …, 2021 - ieeexplore.ieee.org
Since its renaissance, deep learning has been widely used in various medical imaging tasks
and has achieved remarkable success in many medical imaging applications, thereby …

Eleven grand challenges in single-cell data science

D Lähnemann, J Köster, E Szczurek, DJ McCarthy… - Genome biology, 2020 - Springer
The recent boom in microfluidics and combinatorial indexing strategies, combined with low
sequencing costs, has empowered single-cell sequencing technology. Thousands—or even …

Artificial intelligence-based multi-omics analysis fuels cancer precision medicine

X He, X Liu, F Zuo, H Shi, J Jing - Seminars in Cancer Biology, 2023 - Elsevier
With biotechnological advancements, innovative omics technologies are constantly
emerging that have enabled researchers to access multi-layer information from the genome …

Artificial intelligence in digital pathology—new tools for diagnosis and precision oncology

K Bera, KA Schalper, DL Rimm, V Velcheti… - Nature reviews Clinical …, 2019 - nature.com
In the past decade, advances in precision oncology have resulted in an increased demand
for predictive assays that enable the selection and stratification of patients for treatment. The …

Applications of machine learning in drug discovery and development

J Vamathevan, D Clark, P Czodrowski… - Nature reviews Drug …, 2019 - nature.com
Drug discovery and development pipelines are long, complex and depend on numerous
factors. Machine learning (ML) approaches provide a set of tools that can improve discovery …

Hover-net: Simultaneous segmentation and classification of nuclei in multi-tissue histology images

S Graham, QD Vu, SEA Raza, A Azam, YW Tsang… - Medical image …, 2019 - Elsevier
Nuclear segmentation and classification within Haematoxylin & Eosin stained histology
images is a fundamental prerequisite in the digital pathology work-flow. The development of …

Enhancing head and neck tumor management with artificial intelligence: Integration and perspectives

NN Zhong, HQ Wang, XY Huang, ZZ Li, LM Cao… - Seminars in Cancer …, 2023 - Elsevier
Head and neck tumors (HNTs) constitute a multifaceted ensemble of pathologies that
primarily involve regions such as the oral cavity, pharynx, and nasal cavity. The intricate …

Artificial intelligence in diagnostic pathology

S Shafi, AV Parwani - Diagnostic pathology, 2023 - Springer
Digital pathology (DP) is being increasingly employed in cancer diagnostics, providing
additional tools for faster, higher-quality, accurate diagnosis. The practice of diagnostic …