In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …

The theta rhythm is one of the largest and most sinusoidal activity patterns in the brain. Here
I survey progress in the field of theta rhythms research. I present arguments supporting the …

INTRODUCTION SHANK3 is a scaffolding protein that is enriched in postsynaptic densities
of excitatory synapses but ubiquitously expressed in most cells. SHANK3 gene mutations …

The action potential of the squid giant axon is formed by just two voltage-dependent
conductances in the cell membrane, yet mammalian central neurons typically express more …

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels comprise a small
subfamily of proteins within the superfamily of pore-loop cation channels. In mammals, the …

▪ Abstract Hyperpolarization-activated cation currents, termed If, Ih, or Iq, were initially
discovered in heart and nerve cells over 20 years ago. These currents contribute to a wide …

Hippocampal theta rhythm arises from a combination of recently described intrinsic theta
oscillators and inputs from multiple brain areas. Interneurons expressing the markers …

Step hyperpolarizations evoked slowly activating, noninactivating, and slowly deactivating
inward currents from membrane patches recorded in the cell-attached patch configuration …

Both circuit and single-cell properties contribute to network rhythms. In vitro, pyramidal cells
exhibit theta-band membrane potential (subthreshold) resonance, but whether and how …

The vast diversity of GABAergic interneurons is believed to endow hippocampal
microcircuits with the required flexibility for memory encoding and retrieval. However …