Cognitive impairment in older adults: epidemiology, diagnosis, and treatment

NP Palmer, BT Ortega, P Joshi - Psychiatric Clinics, 2022 - psych.theclinics.com
With an increasingly aging population, health care providers will treat a higher number of
patients with cognitive impairment. Identifying cognitive impairment and intervening early …

Moving Towards Ethical-Practical Recommendations for Alzheimer's Disease Prediction: Addressing Interindividual, Interprofessional, and Societal Aspects

S Schicktanz, Z Alpinar-Segawa… - Journal of …, 2024 - journals.sagepub.com
Biomarkers for predicting Alzheimer's disease (AD) are advancing and their implementation
in various healthcare systems is imminent. There is a need for ethical standards addressing …

REM sleep behavior disorder as a pathway to dementia: if, when, how, what, and why should physicians disclose the diagnosis and risk for dementia

RG Malkani, NS Wenger - Current Sleep Medicine Reports, 2021 - Springer
Abstract Purpose of Review People with isolated REM (rapid eye movement) sleep behavior
disorder (iRBD) have a high lifetime risk of developing a neurodegenerative disease …

Ethical issues in genomics research in persons with Alzheimer's Disease/Alzheimer's Disease-related dementia (AD/ADRD): a systematic review

A Yakubu, I Adedeji, OC Maduka, A Jegede… - BMC Medical …, 2024 - Springer
Introduction Given the growing number of Alzheimer's Disease and Alzheimer's Disease
Related Dementias (AD/ADRD) genomics research projects and the vulnerabilities of study …

“I Want to Know Everything...”: The Return of Research Results and the Importance of Transparency in the Acceptability of Lumbar Punctures for African American …

SR Passmore, C Longhurst, A Gerbitz… - Journal of …, 2023 - content.iospress.com
Background: Although African Americans experience the highest risk of Alzheimer's disease
(AD), they are dramatically underrepresented in preclinical biomarker research. This is …

Genome sequencing among children with medical complexity: what constitutes value from parents' perspective?

W Lee, S Luca, G Costain, M Snell… - Journal of Genetic …, 2022 - Wiley Online Library
Genome sequencing (GS) has demonstrated high diagnostic yield in pediatric patients with
complex, clinically heterogeneous presentations. Emerging evidence shows generally …

In-depth analyses of lncRNA and circRNA expression in the hippocampus of LPS-induced AD mice by Byu d Mar 25

Y Zhang, L Tang, Y Wang, X Zhu, L Liu - NeuroReport, 2024 - journals.lww.com
Abstract Byu d Mar 25 (BM25) has been verified to have neuroprotective effects in
Alzheimer's disease (AD) mice. However, the molecular mechanism remains unclear. We …

Predictive testing for neurodegenerative diseases in the age of next‐generation sequencing

J Goldman, S Xie, D Green, A Naini… - Journal of genetic …, 2021 - Wiley Online Library
The availability and cost of next‐generation sequencing (NSG) now allow testing large
numbers of genes simultaneously. However, the gold standard for predictive testing has …

Piecing Together the Alzheimer's Puzzle: Lecanemab's Role in Treatment

DA Ashraf, H Tariq, FS Hassan, F Kamran… - Neurodegenerative …, 2023 - Taylor & Francis
Globally, 47 million individuals live with dementia, and by 2050, that number is expected to
more than triple (to 131 million). One of the main causes of increasing dementia is …

Medications and laboratory testing.

AD Rae-Grant - 2024 - psycnet.apa.org
People being evaluated by a neuropsychologist for neurocognitive disorders may also be
undergoing testing or treatment by primary care physicians, neurologists, or psychiatrists …