Inflammation, immune activation, and antiretroviral therapy in HIV
CO Hileman, NT Funderburg - Current Hiv/aids reports, 2017 - Springer
Abstract Purpose of Review This review focuses on the differential effects of contemporary
antiretrovirals on systemic inflammation as heightened immune activation is linked to …
antiretrovirals on systemic inflammation as heightened immune activation is linked to …
HIV-1–associated atherosclerosis: unraveling the missing link
Cardiovascular disease, including atherosclerosis and atherosclerosis-associated
complications, is an increasing cause of morbidity and mortality in human immunodeficiency …
complications, is an increasing cause of morbidity and mortality in human immunodeficiency …
Chitinase-3-like 1 protein complexes modulate macrophage-mediated immune suppression in glioblastoma
Glioblastoma (GBM), the most common and lethal primary brain tumor, with a median
survival rate of only 15 months, remains incurable despite intensive multimodal treatment of …
survival rate of only 15 months, remains incurable despite intensive multimodal treatment of …
Elevated levels of monocyte activation markers are associated with subclinical atherosclerosis in men with and those without HIV infection
RA McKibben, JB Margolick… - The Journal of …, 2015 - academic.oup.com
Background. Heightened immune activation among human immunodeficiency virus (HIV)–
infected persons may contribute to atherosclerosis. We assessed associations of serologic …
infected persons may contribute to atherosclerosis. We assessed associations of serologic …
Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques
SR Langley, K Willeit, A Didangelos… - The Journal of …, 2017 - Am Soc Clin Investig
BACKGROUND. The identification of patients with high-risk atherosclerotic plaques prior to
the manifestation of clinical events remains challenging. Recent findings question histology …
the manifestation of clinical events remains challenging. Recent findings question histology …
Association of macrophage inflammation biomarkers with progression of subclinical carotid artery atherosclerosis in HIV-infected women and men
Background. Monocytes and monocyte-derived macrophages promote atherosclerosis
through increased inflammation and vascular remodeling. This may be especially true in …
through increased inflammation and vascular remodeling. This may be especially true in …
Evolutionary aspects of macrophages polarization
Macrophages constitute a heterogeneous population of myeloid cells that are essential for
maintaining homeostasis and as a first line of innate responders controlling and organizing …
maintaining homeostasis and as a first line of innate responders controlling and organizing …
Differential reduction in monocyte activation and vascular inflammation with integrase inhibitor–based initial antiretroviral therapy among HIV-infected individuals
CO Hileman, B Kinley, V Scharen-Guivel… - The Journal of …, 2015 - academic.oup.com
Background. Little is known about how different antiretrovirals effect inflammation and
monocyte activation in human immunodeficiency virus (HIV) infection. Methods. We …
monocyte activation in human immunodeficiency virus (HIV) infection. Methods. We …
Extracellular Matrix‐Bioinspired Anisotropic Topographical Cues of Electrospun Nanofibers: A Strategy of Wound Healing through Macrophage Polarization
The skin serves as the body's outermost barrier and is the largest organ, providing protection
not only to the body but also to various internal organs. Owing to continuous exposure to …
not only to the body but also to various internal organs. Owing to continuous exposure to …
Serum levels of galectin-1, galectin-3, and galectin-9 are associated with large artery atherosclerotic stroke
XW He, WL Li, C Li, P Liu, YG Shen, M Zhu, XP Jin - Scientific reports, 2017 - nature.com
The aim of this study was to assess the expression patterns of serum galectin-1 (Gal-1),
galectin-3 (Gal-3), galectin-9 (Gal-9), and galectin-3 binding protein (Gal-3BP) and their …
galectin-3 (Gal-3), galectin-9 (Gal-9), and galectin-3 binding protein (Gal-3BP) and their …