One of the malignant tumors in women that has involved both developed and developing
countries is breast cancer. Similar to other types of tumors, breast cancer cells demonstrate …

Breast cancer (BC) is one of the most common cancers in women worldwide; however, the
successful treatment of BC, especially triple-negative breast cancer (TNBC), remains a …

Pyroptosis is a proinflammatory form of programmed cell death that results in the release of
cellular contents and activation of immune responses. However, GSDME (a pyroptosis …

Aims To explore the hepatoprotective role of quercetin and its novel molecular mechanism
of action on breast cancer associated hepatic inflammation and fibrosis via Vitamin D …

Increased glycolysis is one of the key metabolic hallmarks of cancer cells. However, the
roles of lncRNAs in energy metabolism and cancer metastasis remain unclear. Here, the …

Metastatic tumor is initiated by metastatic seeds (cancer stem cells “CSCs”) in a controlled
redox microenvironment. Hence, an effective therapy that disrupts redox balance with …

Tumor-associated macrophages (TAMs), the most abundant immune cells in the tumor
microenvironment (TME), profoundly affect the occurrence and development of tumors. To …

The genetic alterations contributing to migration proficiency, a phenotypic hallmark of
metastatic cells required for colonizing distant organs, remain poorly defined. Here, we used …

Breast cancer is the leading cause of cancer-related deaths in females worldwide, and the
liver is one of the most common sites of distant metastases in breast cancer patients …

RUNX1 has long known for its role in hematopoiesis until recently it is implicated in human
breast cancer pathogenesis. This has drawn attention in research as elevated expression of …