Abstract Glycogen synthase kinase‐3 (GSK3) is a highly evolutionarily conserved
serine/threonine protein kinase first identified as an enzyme that regulates glycogen …

Glycogen is a branched polymer of glucose that acts as a store of energy in times of
nutritional sufficiency for utilization in times of need. Its metabolism has been the subject of …

Diabetic nephropathy (DN) is the most common cause of end-stage kidney disease
worldwide, and is associated with increased morbidity and mortality in patients with both …

This paper presents the 12th update of the human obesity gene map, which incorporates
published results up to the end of October 2005. Evidence from single‐gene mutation …

Abstract Glycogen synthase kinase-3 (GSK-3) is an unusual protein-serine kinase in that it is
primarily regulated by inhibition and lies downstream of multiple cell signaling pathways …

Deciphering what governs inflammation and its effects on tissues is vital for understanding
many pathologies. The recent discovery that glycogen synthase kinase-3 (GSK3) promotes …

Glycogen synthase kinase 3 (GSK3), a constitutively acting multi‐functional serine threonine
kinase is involved in diverse physiological pathways ranging from metabolism, cell cycle …

The inactivation of glycogen synthase kinase (GSK) 3 has been proposed to play important
roles in insulin and Wnt signalling. To define the role that inactivation of GSK3 plays, we …

The ever-increasing prevalence of noncommunicable diseases (NCDs) represents a major
public health burden worldwide. The most common form of NCD is metabolic diseases …

Alzheimer's disease (AD) is a prevalent neurodegenerative disease predominantly affecting
millions of elderly people. To date, no effective therapy has been identified to reverse the …