Since the initial description of apoptosis, a number of different forms of cell death have been
described. In this review we will focus on classic caspase-dependent apoptosis and its …

The emergence and takeover of hepatitis B virus (HBV) variants carrying mutation (s) in the
preS/S genomic region is a fairly frequent event that may occur spontaneously or may be the …

Abstract Background Hepatitis B virus (HBV) is the leading cause of liver cancer, but the
mechanisms by which HBV causes liver cancer are poorly understood and …

Chronic hepatitis B virus (HBV) infection remains the number one risk factor for
hepatocellular carcinoma (HCC), accounting for more than 600 000 deaths/year. Despite …

Hepatitis B virus (HBV) causes chronic hepatitis in hundreds of millions of people worldwide,
which can eventually lead to hepatocellular carcinoma (HCC). The molecular mechanisms …

Chronic hepatitis B virus (HBV) infection is one of the most common factors associated with
hepatocellular carcinoma (HCC), which is the sixth most prevalent cancer among all cancers …

Abstract Background: Hepatitis B virus (HBV) causes both acute and chronic liver injury.
Viral proteins are involved in the pathological progress. Hepatitis B core antigen (HBcAg), a …

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the
TNF superfamily, and has been identified as a novel mediator of fatty liver disease (FLD) …

Background There are around 350 million of hepatitis B surface antigen (HBsAg) carriers
worldwide, and among them, high risk of developing hepatocellular carcinoma (HCC) has …

Highlights•Chronic HBV infection is the most common chronic viral infection in the
world.•Chronic HBV carriers (CHB) are at high risk for liver cirrhosis and HCC.•Despite …