Pathophysiological molecular mechanisms of obesity: a link between MAFLD and NASH with cardiovascular diseases

J Gutiérrez-Cuevas, A Santos… - International Journal of …, 2021 - mdpi.com
Obesity is now a worldwide epidemic ensuing an increase in comorbidities' prevalence,
such as insulin resistance, type 2 diabetes (T2D), metabolic dysfunction-associated fatty …

Impact of dysfunctional adipose tissue depots on the cardiovascular system

R D'Oria, VA Genchi, C Caccioppoli… - International journal of …, 2022 - mdpi.com
Obesity with its associated complications represents a social, economic and health problem
of utmost importance worldwide. Specifically, obese patients carry a significantly higher risk …

Hepatic mitochondria-gut microbiota interactions in metabolism-associated fatty liver disease

F Bellanti, A Lo Buglio, G Vendemiale - Metabolites, 2023 - mdpi.com
The prevalence of metabolism-associated fatty liver disease (MAFLD) represents an urgent
pandemic, complicated by a higher risk of morbidity and mortality as well as an increased …

Mitochondrial dysfunction-associated mechanisms in the development of chronic liver diseases

MK Arumugam, T Gopal, RR Kalari Kandy… - Biology, 2023 - mdpi.com
Simple Summary Mitochondria are crucially important organelles involved in various
metabolic activities, including energy generation. The involvement of mitochondrial …

[HTML][HTML] Pathophysiological mechanisms of cardiovascular disorders in non-alcoholic fatty liver disease

DV Garbuzenko - Gastroenterology and Hepatology from Bed to …, 2022 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease is one of the main liver diseases worldwide. The most
common cause of death in patients with nonalcoholic fatty liver disease is cardiovascular …

The newly proposed alanine aminotransferase to high-density lipoprotein cholesterol ratio has shown effectiveness in identifying non-alcoholic fatty liver disease

J Qiu, M Kuang, R Yang, C Yu, S He… - Frontiers in …, 2023 - frontiersin.org
Objective Alanine aminotransferase (ALT) and high-density lipoprotein cholesterol (HDL-C)
are important predictive factors for non-alcoholic fatty liver disease (NAFLD). The aim of this …

Deciphering the molecular pathways of saroglitazar: A dual PPAR α/γ agonist for managing metabolic NAFLD

D Ezhilarasan - Metabolism, 2024 - Elsevier
Saroglitazar (SARO), a dual peroxisome proliferator activated receptor (PPAR)-α/γ agonist,
has been used to treat metabolic diseases such as insulin resistance and diabetic …

Frizzled receptors and SFRP5 in lipid metabolism: current findings and potential applications

DT Chu, TL Nguyen - Progress in Molecular Biology and Translational …, 2023 - Elsevier
Lipid metabolism plays a very important role as the central metabolic process of the body.
Lipid metabolism interruptions may cause many chronic diseases, for example, non …

Abnormal metabolism in hepatic stellate cells: Pandora's box of MAFLD related hepatocellular carcinoma

Y Sun, H Zhang, Y Li, J Han - Biochimica et Biophysica Acta (BBA)-Reviews …, 2024 - Elsevier
Metabolic associated fatty liver disease (MAFLD) is a significant risk factor for the
development of hepatocellular carcinoma (HCC). Hepatic stellate cells (HSCs), as key …

[HTML][HTML] Steamed daylily flower (Hemerocallis fulva L.) protected cardiac and hepatic cells against ethanol induced apoptotic and oxidative damage

SL Yan, WT Wu, MC Mong, MC Yin - Journal of Food and Drug …, 2023 - ncbi.nlm.nih.gov
Our previous study examined the phytochemical composition and bio-activities of raw daylily
flower (Hemerocallis fulva L.). However, this plant food is usually served via heat process …