Translational opportunities in animal and human models to study alcohol use disorder
Animal and human laboratory paradigms offer invaluable approaches to study the complex
etiologies and mechanisms of alcohol use disorder (AUD). We contend that human …
etiologies and mechanisms of alcohol use disorder (AUD). We contend that human …
Resurgence of ethanol seeking following voluntary abstinence produced by nondrug differential reinforcement of other behavior
AR Craig, CN Agnew, KE Derrenbacker… - Journal of the …, 2024 - Wiley Online Library
Resurgence refers to the relapse of a target behavior following the worsening of a source of
alternative reinforcement that was made available during response elimination. Most …
alternative reinforcement that was made available during response elimination. Most …
[HTML][HTML] Understanding sex differences and the translational value of models of persistent substance use despite negative consequences
Persistent substance use despite negative consequences is a key facet of substance use
disorder. The last decade has seen the preclinical field adopt the use of punishment to …
disorder. The last decade has seen the preclinical field adopt the use of punishment to …
The influence of chromosome 4 on high ethanol consumption and blood pressure
PAR Anjos, RCN Marchette, R Kremer, N Granzotto… - Alcohol, 2022 - Elsevier
Abstract The Spontaneously Hypertensive Rats (SHR) strain was developed through
selective breeding for high systolic blood pressure. In our laboratory, we established a …
selective breeding for high systolic blood pressure. In our laboratory, we established a …
Sex-dependent effects of chronic stress on punished cocaine self-administration and cue-induced relapse to cocaine seeking
H Edson, KT Ball - Physiology & Behavior, 2022 - Elsevier
We tested the effects of chronic stress on cocaine relapse after drug-reinforced responding
was suppressed by punishment, an animal model of human relapse after self-imposed …
was suppressed by punishment, an animal model of human relapse after self-imposed …
Abstinence as Choice: Exploring Voluntary Abstinence from Alcohol Self-Administration Using the Resurgence-as-Choice Framework
Resurgence is an increase in the rate of a previously suppressed behavior that occurs when
an alternative source of reinforcement is made worse in some way. The Resurgence as …
an alternative source of reinforcement is made worse in some way. The Resurgence as …
Resurgence and Behavioral Contrast, Compared and Contrasted
KA Lattal, AK Miles - Perspectives on Behavior Science, 2024 - Springer
This is a review of the relation between operant response resurgence and behavioral
contrast. Both are defined by rate changes in a target response as a function of …
contrast. Both are defined by rate changes in a target response as a function of …
Evaluating voluntary abstinence from ethanol self-administration in rats using a concurrent-chains procedure
CN Agnew, WE Sullivan, KE Derrenbacker… - Learning and …, 2024 - Elsevier
This pilot study aimed to examine voluntary abstinence from, and relapse of, ethanol
seeking following removal of alternative nondrug reinforcement using a concurrent-chains …
seeking following removal of alternative nondrug reinforcement using a concurrent-chains …
Drug versus non‐drug behaviors: A dual‐reward model of sex differences and neurobiological mechanisms in rats
RW Nall, RM Chalhoub… - Journal of the …, 2022 - Wiley Online Library
Substance Use Disorders (SUDs) are an impactful problem characterized by chronic relapse
and engagement in drug‐related behaviors at the expense of non‐drug behaviors. Brain …
and engagement in drug‐related behaviors at the expense of non‐drug behaviors. Brain …
A Comparison of the Relative Magnitude of Combinations of Relapse Types in Rats
M Bridges - 2024 - digitalcommons.jsu.edu
Applied behavior analysis uses scientifically derived methods to create treatments for
socially significant behaviors. A threat to these successful treatments is the recurrence of …
socially significant behaviors. A threat to these successful treatments is the recurrence of …