[HTML][HTML] 3D approaches to model the tumor microenvironment of pancreatic cancer
In tumor engineering, 3D approaches are used to model components of the tumor
microenvironment and to test new treatments. Pancreatic cancers are a cancer of substantial …
microenvironment and to test new treatments. Pancreatic cancers are a cancer of substantial …
Theranostics targeting fibroblast activation protein in the tumor stroma: 64Cu-and 225Ac-labeled FAPI-04 in pancreatic cancer xenograft mouse models
T Watabe, Y Liu, K Kaneda-Nakashima… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Fibroblast activation protein (FAP), which promotes tumor growth and progression, is
overexpressed in cancer-associated fibroblasts of many human epithelial cancers. Because …
overexpressed in cancer-associated fibroblasts of many human epithelial cancers. Because …
Molecular regulatory roles of long non-coding RNA HOTTIP: an overview in gastrointestinal cancers
Gastrointestinal (GI) cancers presented an alarmingly high number of new cancer cases
worldwide and are highly characterised by poor prognosis. The poor overall survival is …
worldwide and are highly characterised by poor prognosis. The poor overall survival is …
[HTML][HTML] Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types
Cancer cell lines are a cornerstone of cancer research but previous studies have shown that
not all cell lines are equal in their ability to model primary tumors. Here we present a …
not all cell lines are equal in their ability to model primary tumors. Here we present a …
Surface Engineering of Natural Killer Cells with CD44‐targeting Ligands for Augmented Cancer Immunotherapy
Adoptive immunotherapy utilizing natural killer (NK) cells has demonstrated remarkable
efficacy in treating hematologic malignancies. However, its clinical intervention for solid …
efficacy in treating hematologic malignancies. However, its clinical intervention for solid …
pH-sensitive nanodrug carriers for codelivery of ERK inhibitor and gemcitabine enhance the inhibition of tumor growth in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC), a metabolic disorder, remains one of the
leading cancer mortality sources worldwide. An initial response to treatments, such as …
leading cancer mortality sources worldwide. An initial response to treatments, such as …
Critical parameters to improve pancreatic cancer treatment using magnetic hyperthermia: Field conditions, immune response, and particle biodistribution
Magnetic hyperthermia (MH) was used to treat a murine model of pancreatic cancer. This
type of cancer is generally characterized by the presence of dense stroma that acts as a …
type of cancer is generally characterized by the presence of dense stroma that acts as a …
Continued exploration of 1, 2, 4-oxadiazole periphery for carbonic anhydrase-targeting primary arene sulfonamides: Discovery of subnanomolar inhibitors of …
An expanded set of diversely substituted 1, 2, 4-oxadiazole-containing primary aromatic
sulfonamides was synthesized and tested for inhibition of human carbonic anhydrase I, II, IX …
sulfonamides was synthesized and tested for inhibition of human carbonic anhydrase I, II, IX …
Quantitative monitoring of circulating tumor DNA in patients with advanced pancreatic cancer undergoing chemotherapy
M Sugimori, K Sugimori, H Tsuchiya, Y Suzuki… - Cancer …, 2020 - Wiley Online Library
According to cancer genome sequences, more than 90% of cases of pancreatic ductal
adenocarcinoma (PDAC) harbor active KRAS mutations. Digital PCR (dPCR) enables …
adenocarcinoma (PDAC) harbor active KRAS mutations. Digital PCR (dPCR) enables …
[HTML][HTML] Gene expression comparison between the lymph node-positive and-negative reveals a peculiar immune microenvironment signature and a theranostic role …
A Argentiero, S De Summa, R Di Fonte, RM Iacobazzi… - Cancers, 2019 - mdpi.com
Over the past several years there has been much debate with regards to the prognostic and
clinical significance of pancreatic ductal adenocarcinoma (PDAC) with lymph nodes …
clinical significance of pancreatic ductal adenocarcinoma (PDAC) with lymph nodes …