Radiopharmaceuticals for PET and SPECT imaging: a literature review over the last decade

G Crișan, NS Moldovean-Cioroianu… - International journal of …, 2022 - mdpi.com
Positron emission tomography (PET) uses radioactive tracers and enables the functional
imaging of several metabolic processes, blood flow measurements, regional chemical …

Small-molecule probes from bench to bedside: advancing molecular analysis of drug–target interactions toward precision medicine

S Pan, A Ding, Y Li, Y Sun, Y Zhan, Z Ye… - Chemical Society …, 2023 - pubs.rsc.org
Over the past decade, remarkable advances have been witnessed in the development of
small-molecule probes. These molecular tools have been widely applied for interrogating …

[HTML][HTML] Biodistribution, pharmacokinetics and excretion studies of intravenously injected nanoparticles and extracellular vesicles: Possibilities and challenges

T Skotland, TG Iversen, A Llorente, K Sandvig - Advanced drug delivery …, 2022 - Elsevier
There is a large interest in developing nanoparticles and extracellular vesicles for delivery of
therapeutics or imaging agents. Regulatory approval of such products requires knowledge …

Recent developments in SPECT/CT

P Ritt - Seminars in Nuclear Medicine, 2022 - Elsevier
The debut of multimodal Single Photon Emission Computed Tomography/X-ray Computed
Tomography (SPECT/CT) has signified an important advancement of Nuclear Medicine …

Review on 99mTc radiopharmaceuticals with emphasis on new advancements

A Duatti - Nuclear medicine and biology, 2021 - Elsevier
Rapid imaging acquisition, high spatial resolution and sensitivity, powered by
advancements in solid-state detector technology, are significantly changing the perspective …

SPECT/CT: Standing on the shoulders of giants, it is time to reach for the sky!

T Van den Wyngaert, F Elvas… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Twenty years ago, SPECT/CT became commercially available, combining the strengths of
both techniques: the diagnostic sensitivity of SPECT and the anatomic detail of CT. Other …

Imaging blood-brain barrier dysfunction: A state-of-the-art review from a clinical perspective

P Moyaert, BE Padrela, CA Morgan, J Petr… - Frontiers in aging …, 2023 - frontiersin.org
The blood-brain barrier (BBB) consists of specialized cells that tightly regulate the in-and
outflow of molecules from the blood to brain parenchyma, protecting the brain's …

Dendrimers based cancer nanotheranostics: An overview

V Saluja, Y Mishra, V Mishra, N Giri, P Nayak - International Journal of …, 2021 - Elsevier
Cancer is a known deadliest disease that requires a judicious diagnostic, targeting, and
treatment strategy for an early prognosis and selective therapy. The major pitfalls of the …

What scans we will read: imaging instrumentation trends in clinical oncology

T Beyer, L Bidaut, J Dickson, M Kachelriess… - Cancer Imaging, 2020 - Springer
Oncological diseases account for a significant portion of the burden on public healthcare
systems with associated costs driven primarily by complex and long-lasting therapies …

Molecular Imaging Diagnosis of Renal Cancer Using 99mTc-Sestamibi SPECT/CT and Girentuximab PET-CT-Current Evidence and Future Development of Novel …

OS Tataru, M Marchioni, F Crocetto, B Barone… - Diagnostics, 2023 - mdpi.com
Novel molecular imaging opportunities to preoperatively diagnose renal cell carcinoma is
under development and will add more value in limiting the postoperative renal function loss …