Emerging nanomedicines strategies focused on tumor microenvironment against cancer recurrence and metastasis

Y Feng, Z Liao, H Zhang, X Xie, F You, X Liao… - Chemical Engineering …, 2023 - Elsevier
Every stage of cancer metastasis, immune surveillance evasion, and therapeutic resistance
is influenced by tumor microenvironment (TME). In light of this, nanomedicines design based …

Current advance of nanotechnology in diagnosis and treatment for malignant tumors

B Wang, S Hu, Y Teng, J Chen, H Wang, Y Xu… - … and Targeted Therapy, 2024 - nature.com
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

Dissolvable Self‐Locking Microneedle Patches Integrated with Immunomodulators for Cancer Immunotherapy

SH Joo, J Kim, J Hong, S Fakhraei Lahiji… - Advanced …, 2023 - Wiley Online Library
Advancements in micro‐resolution 3D printers have significantly facilitated the development
of highly complex mass‐producible drug delivery platforms. Conventionally, due to the …

Developing a gallium (III) agent based on the properties of the tumor microenvironment and lactoferrin: achieving two-agent co-delivery and multi-targeted …

T Yang, Z Zhang, J Zhang, Y Li, W Li… - Journal of Medicinal …, 2022 - ACS Publications
To develop a next-generation anticancer metal-based drug, realize the multi-targeted
combination therapy of protein drug and metal-based drug for cancer, solve their co-delivery …

Photothermal-triggered dendrimer nanovaccines boost systemic antitumor immunity

S Shen, Y Gao, Z Ouyang, B Jia, M Shen… - Journal of Controlled …, 2023 - Elsevier
Tumor vaccine that can effectively activate or strengthen the body's antitumor immune
response to kill and eliminate tumor cells has attracted widespread attention. Currently …

Drug-drug conjugates self-assembled nanomedicines triggered photo−/immuno-therapy for synergistic cancer treatments

H Qu, L Li, H Chen, M Tang, W Cheng, T Lin… - Journal of Controlled …, 2023 - Elsevier
Although immunotherapies have made progress in cancer treatment, their clinical response
rates vary widely and are typically low due to sparse immune cell infiltration (immune “cold”) …

PD-1/PD-L1 inhibitors in patients with preexisting autoimmune diseases

K Zhang, X Kong, Y Li, Z Wang, L Zhang… - Frontiers in …, 2022 - frontiersin.org
Autoimmune diseases and malignant tumors are the two hotspots and difficulties that are
currently being studied and concerned by the medical field. The use of PD-1/PD-L1 …

In situ cocktail nanovaccine for cancer immunotherapy

M Liu, D Xie, D Hu, R Zhang, Y Wang, L Tang… - Advanced …, 2023 - Wiley Online Library
In situ vaccination is a desirable strategy for cancer immunotherapy due to its convenience
and capacity to target tumor antigens. Here, an in situ nanovaccine based on a cationic …

Application of nanoparticles in the treatment of lung cancer with emphasis on receptors

J Wang, T Zhou, Y Liu, S Chen, Z Yu - Frontiers in pharmacology, 2022 - frontiersin.org
Lung cancer is one of the malignant tumors that has seen the most rapid growth in terms of
morbidity and mortality in recent years, posing the biggest threat to people's health and lives …

[HTML][HTML] Polymersomes as a potential platform for cancer immunotherapy

JF Scheerstra, AC Wauters, J Tel… - Materials Today …, 2022 - Elsevier
With the focus in the field of cancer nanomedicine shifting from direct tumor targeting to
modulation of the immune system, new opportunities arise for the employment of …