Understanding rotavirus vaccine efficacy and effectiveness in countries with high child mortality

T Varghese, G Kang, AD Steele - Vaccines, 2022 - mdpi.com
Rotavirus claims thousands of lives of children globally every year with a disproportionately
high burden in low-and lower-middle income countries where access to health care is …

The Full Impact of Rotavirus Vaccines in Africa Has Yet to Be Realized

AD Steele, GE Armah, JM Mwenda… - Clinical Infectious …, 2023 - academic.oup.com
Africa bears the brunt of diarrheal mortality globally. Rotavirus vaccination rates are high
across the continent and demonstrate impact on diarrheal disease reduction. Nevertheless …

Secretors of HBGA and susceptibility to norovirus and rotavirus diarrhea

H Faden, BA Schaefer - The Pediatric Infectious Disease Journal, 2021 - journals.lww.com
Histo-blood group antigen contains oligosaccharides that serve as receptors for norovirus
(NoV) and rotavirus (RV). The receptors are only present on the surface of intestinal mucosal …

Epidemiological trends of five common diarrhea-associated enteric viruses pre-and post-rotavirus vaccine introduction in coastal Kenya

AW Lambisia, S Onchaga, N Murunga, CS Lewa… - Pathogens, 2020 - mdpi.com
Using real-time RT-PCR, we screened stool samples from children aged< 5 years
presenting with diarrhea and admitted to Kilifi County Hospital, coastal Kenya, pre-(2003 …

Rotavirus group A genotype circulation patterns across Kenya before and after nationwide vaccine introduction, 2010–2018

MJ Mwanga, BE Owor, JB Ochieng, MH Ngama… - BMC infectious …, 2020 - Springer
Background Kenya introduced the monovalent G1P [8] Rotarix® vaccine into the infant
immunization schedule in July 2014. We examined trends in rotavirus group A (RVA) …

Differences in epidemiology of enteropathogens in children pre-and post-rotavirus vaccine introduction in Kilifi, coastal Kenya

CN Agoti, MD Curran, N Murunga, M Ngari… - Gut Pathogens, 2022 - Springer
Abstract Background Kenya introduced Rotarix®(GlaxoSmithKline Biologicals, Rixensart,
Belgium) vaccination into its national immunization programme beginning July 2014. The …

[图书][B] Vaccination programmes: epidemiology, monitoring, evaluation

S Hahné, K Bollaerts, P Farrington - 2021 - taylorfrancis.com
Vaccination programmes are of vital importance to public health and are present in virtually
every country in the world. By promoting an understanding of the diverse effects of …

Decision-making process for introduction of maternal vaccines in Kenya, 2017–2018

NA Otieno, FA Malik, SW Nganga, WN Wairimu… - Implementation …, 2021 - Springer
Background Maternal immunization is a key strategy for reducing morbidity and mortality
associated with infectious diseases in mothers and their newborns. Recent developments in …

[HTML][HTML] Mortality in rural coastal Kenya measured using the Kilifi Health and Demographic Surveillance System: a 16-year descriptive analysis

M Otiende, E Bauni, A Nyaguara, D Amadi… - Wellcome open …, 2021 - ncbi.nlm.nih.gov
Background: The Kilifi Health and Demographic Surveillance System (KHDSS) was
established in 2000 to define the incidence and prevalence of local diseases and evaluate …

Multiple introductions and predominance of rotavirus group a genotype G3P [8] in Kilifi, coastal Kenya, 4 years after nationwide vaccine introduction

MJ Mwanga, JR Verani, R Omore, JE Tate… - Pathogens, 2020 - mdpi.com
Globally, rotavirus group A (RVA) remains a major cause of severe childhood diarrhea,
despite the use of vaccines in more than 100 countries. RVA sequencing for local outbreaks …